caa a22 4500 606178376 CHVBK 20210128100756.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s11136-015-0943-5 doi (NATIONALLICENCE)springer-10.1007/s11136-015-0943-5 Quality of life in a community sample of young cocaine and/or heroin users: the role of mental disorders [Elektronische Daten] [M. Chahua, A. Sánchez-Niubò, M. Torrens, L. Sordo, M. Bravo, M. Brugal, A. Domingo-Salvany] Purpose: Drug addiction and psychiatric disorders are frequently concomitant; however, few studies have investigated the impact of psychiatric disorders other than substance use disorder (SUD) on health-related quality of life (HRQoL) in drug users not in treatment. We studied the association of psychiatric disorders other than SUD with HRQoL in a street-recruited sample of cocaine and/or heroin users. Methods: It is a cross-sectional study involving 287 young users of cocaine and/or heroin in Barcelona, Spain. HRQoL was assessed with the Nottingham health profile (NHP). Patterns of drug use and mental disorders were assessed using the Spanish version of the psychiatric research interview for substance and mental disorders IV, and degree of dependence through the severity of dependence scale (SDS). The association of mental disorders with HRQoL was assessed through a Tobit regression analysis. Results: The overall NHP score was 23.9 (SD=20.5, range 0-91.7). Sixty-one percent of the sample had two or more SUDs; 22% had at least one non-SUD Axis I disorder (anxiety, mood, psychotic, or eating disorder); and 27.2% had a borderline personality disorder (BPD) and/or antisocial personality disorder. Variables negatively associated with the global NHP score were psychosis [transformed beta coefficient: 15.23; 95% confidence interval [CI] 4.48-25.97], BPD (9.55; 95% CI 2.95-16.15), severity of dependence (8.12; 95% CI 3.37-12.87), having two or more SUDs (for two or three SUDs: 6.83; 95% CI 2.08-11.59) (>3 SUDs: 7.70; 95% CI 1.72-13.68) and the intravenous use of some substance (10.20; 95% CI 6.00-14.40). Conclusion: HRQoL among street-recruited illegal substance users was impaired, particularly among those with psychiatric comorbidity, psychosis, and BPD being especially relevant. Springer International Publishing Switzerland, 2015 Quality of life nationallicence Borderline personality disorder nationallicence Psychotic disorders nationallicence Substance use disorder nationallicence Illicit drug users nationallicence PRISM nationallicence Chahua M. Escuela Nacional de Sanidad, Instituto de Salud Carlos III, Madrid, Spain aut Sánchez-Niubò A. Drug Abuse Epidemiology Research Group, IMIM-Hospital del Mar, Dr Aiguader 88, 08002, Barcelona, Spain aut Torrens M. Addiction Research Group, IMIM-Hospital del Mar, Barcelona, Spain aut Sordo L. Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain aut Bravo M. Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain aut Brugal M. Agència de Salut Pública de Barcelona, Barcelona, Spain aut Domingo-Salvany A. Drug Abuse Epidemiology Research Group, IMIM-Hospital del Mar, Dr Aiguader 88, 08002, Barcelona, Spain aut Quality of Life Research Springer International Publishing 24/9(2015-09-01), 2129-2137 0962-9343 24:9<2129 2015 24 11136 https://doi.org/10.1007/s11136-015-0943-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-0943-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chahua M. Escuela Nacional de Sanidad, Instituto de Salud Carlos III, Madrid, Spain aut NATIONALLICENCE 700 1- Sánchez-Niubò A. Drug Abuse Epidemiology Research Group, IMIM-Hospital del Mar, Dr Aiguader 88, 08002, Barcelona, Spain aut NATIONALLICENCE 700 1- Torrens M. Addiction Research Group, IMIM-Hospital del Mar, Barcelona, Spain aut NATIONALLICENCE 700 1- Sordo L. Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain aut NATIONALLICENCE 700 1- Bravo M. Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, Spain aut NATIONALLICENCE 700 1- Brugal M. Agència de Salut Pública de Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- Domingo-Salvany A. Drug Abuse Epidemiology Research Group, IMIM-Hospital del Mar, Dr Aiguader 88, 08002, Barcelona, Spain aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/9(2015-09-01), 2129-2137 0962-9343 24:9<2129 2015 24 11136