caa a22 4500 606178384 CHVBK 20210128100756.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s11136-015-0948-0 doi (NATIONALLICENCE)springer-10.1007/s11136-015-0948-0 Development of a cross-cultural item bank for measuring quality of life related to mental health in multiple sclerosis patients [Elektronische Daten] [Pierre Michel, Pascal Auquier, Karine Baumstarck, Jean Pelletier, Anderson Loundou, Badih Ghattas, Laurent Boyer] Objective: Quality of life (QoL) measurements are considered important outcome measures both for research on multiple sclerosis (MS) and in clinical practice. Computerized adaptive testing (CAT) can improve the precision of measurements made using QoL instruments while reducing the burden of testing on patients. Moreover, a cross-cultural approach is also necessary to guarantee the wide applicability of CAT. The aim of this preliminary study was to develop a calibrated item bank that is available in multiple languages and measures QoL related to mental health by combining one generic (SF-36) and one disease-specific questionnaire (MusiQoL). Methods: Patients with MS were enrolled in this international, multicenter, cross-sectional study. The psychometric properties of the item bank were based on classical test and item response theories and approaches, including the evaluation of unidimensionality, item response theory model fitting, and analyses of differential item functioning (DIF). Convergent and discriminant validities of the item bank were examined according to socio-demographic, clinical, and QoL features. Results: A total of 1992 patients with MS and from 15 countries were enrolled in this study to calibrate the 22-item bank developed in this study. The strict monotonicity of the Cronbach's alpha curve, the high eigenvalue ratio estimator (5.50), and the adequate CFA model fit (RMSEA=0.07 and CFI=0.95) indicated that a strong assumption of unidimensionality was warranted. The infit mean square statistic ranged from 0.76 to 1.27, indicating a satisfactory item fit. DIF analyses revealed no item biases across geographical areas, confirming the cross-cultural equivalence of the item bank. External validity testing revealed that the item bank scores correlated significantly with QoL scores but also showed discriminant validity for socio-demographic and clinical characteristics. Conclusion: This work demonstrated satisfactory psychometric characteristics for a QoL item bank for MS in multiple languages. This work may offer a common measure for the assessment of QoL in different cultural contexts and for international studies conducted on MS. Springer International Publishing Switzerland, 2015 Multiple sclerosis nationallicence Quality of life nationallicence MusiQoL nationallicence SF-36 nationallicence Item bank nationallicence Computerized adaptive testing nationallicence Michel Pierre Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut Auquier Pascal Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut Baumstarck Karine Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut Pelletier Jean Departments of Neurology and CRMBM CNRS6612, Timone University Hospital APHM, Marseille, France aut Loundou Anderson Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut Ghattas Badih Aix-Marseille Univ - I2M UMR 7373, 13009, Marseille, France aut Boyer Laurent Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut Quality of Life Research Springer International Publishing 24/9(2015-09-01), 2261-2271 0962-9343 24:9<2261 2015 24 11136 https://doi.org/10.1007/s11136-015-0948-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-0948-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Michel Pierre Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut NATIONALLICENCE 700 1- Auquier Pascal Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut NATIONALLICENCE 700 1- Baumstarck Karine Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut NATIONALLICENCE 700 1- Pelletier Jean Departments of Neurology and CRMBM CNRS6612, Timone University Hospital APHM, Marseille, France aut NATIONALLICENCE 700 1- Loundou Anderson Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut NATIONALLICENCE 700 1- Ghattas Badih Aix-Marseille Univ - I2M UMR 7373, 13009, Marseille, France aut NATIONALLICENCE 700 1- Boyer Laurent Aix-Marseille University, EA3279: Public Health, Chronic Diseases and Quality of Life, Research Unit, 13005, Marseille, France aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/9(2015-09-01), 2261-2271 0962-9343 24:9<2261 2015 24 11136