caa a22 4500 606178635 CHVBK 20210128100757.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s11136-014-0910-6 doi (NATIONALLICENCE)springer-10.1007/s11136-014-0910-6 Reliability and validity of the EQ-5D-5L compared to the EQ-5D-3L in patients with osteoarthritis referred for hip and knee replacement [Elektronische Daten] [Barbara Conner-Spady, Deborah Marshall, Eric Bohm, Michael Dunbar, Lynda Loucks, Ammar Khudairy, Tom Noseworthy] Purpose: To assess the test-retest reliability of the EQ-5D-5L (5L) and compare the validity of the 5L and EQ-5D-3L (3L) in osteoarthritis patients referred to an orthopaedic surgeon for total joint replacement. Methods: We mailed questionnaires to 306 consecutive patients following referral and a second questionnaire after 2weeks to assess reliability. Questionnaires included the 5L, EQ-VAS, Short Form-12, Oxford hip and knee scores, pain VAS, and the 3L. We compared the ceiling effect, redistribution properties, convergent and discriminant validity, and discriminatory power of the 5L and 3L. Results: We obtained 176 respondents (response rate 58%), 60% female, 64% knee patients, mean age 65years (SD 11), with no significant differences between responders versus non-responders. Intraclass correlation coefficients were 0.61-0.77 for the 5L dimensions and 0.87 for the 5L index. For the 3L, most patients used level 2 (some/moderate problems) for mobility (87%), usual activities (78%), and pain/discomfort (71%). In comparison, 5L responses were spread out with only 52, 42, and 50%, respectively, using the middle level. All convergent validity coefficients were stronger with the 5L (Spearman coefficients 0.51-0.75). Absolute informativity (Shannon's index) showed higher results for all dimensions of the 5L compared with the 3L (average difference 0.74). Relative informativity (Shannon's evenness index) showed an increase from the 3L to the 5L in mobility, usual activities, and pain/discomfort. Conclusions: The 5L provided stronger validity evidence than the 3L, especially for dimensions relevant to this patient population—mobility, usual activities, and pain/discomfort. Springer International Publishing Switzerland, 2015 EQ-5D-5L nationallicence EQ-5D-3L nationallicence Reliability nationallicence Validity nationallicence Total joint replacement nationallicence Osteoarthritis nationallicence Conner-Spady Barbara Department of Community Health Sciences, University of Calgary, 3rd Floor, TRW Building, 3280 Hospital Drive NW, T2N 4Z6, Calgary, AB, Canada aut Marshall Deborah Department of Community Health Sciences, University of Calgary, 3rd Floor, TRW Building, 3280 Hospital Drive NW, T2N 4Z6, Calgary, AB, Canada aut Bohm Eric Department of Surgery, Faculty of Health Sciences, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut Dunbar Michael Division of Orthopaedic Surgery, Dalhousie University, 1796 Summer Street, B3H 3A7, Halifax, NS, Canada aut Loucks Lynda Concordia Hip and Knee Institute, 310-1155 Concordia Avenue, R2K 2M9, Winnipeg, MB, Canada aut Khudairy Ammar QEII Health Sciences Centre, Dalhousie University, Halifax, NS, Canada aut Noseworthy Tom Department of Community Health Sciences, University of Calgary, 3rd Floor, TRW Building, 3280 Hospital Drive NW, T2N 4Z6, Calgary, AB, Canada aut Quality of Life Research Springer International Publishing 24/7(2015-07-01), 1775-1784 0962-9343 24:7<1775 2015 24 11136 https://doi.org/10.1007/s11136-014-0910-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0910-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Conner-Spady Barbara Department of Community Health Sciences, University of Calgary, 3rd Floor, TRW Building, 3280 Hospital Drive NW, T2N 4Z6, Calgary, AB, Canada aut NATIONALLICENCE 700 1- Marshall Deborah Department of Community Health Sciences, University of Calgary, 3rd Floor, TRW Building, 3280 Hospital Drive NW, T2N 4Z6, Calgary, AB, Canada aut NATIONALLICENCE 700 1- Bohm Eric Department of Surgery, Faculty of Health Sciences, University of Manitoba, R3T 2N2, Winnipeg, MB, Canada aut NATIONALLICENCE 700 1- Dunbar Michael Division of Orthopaedic Surgery, Dalhousie University, 1796 Summer Street, B3H 3A7, Halifax, NS, Canada aut NATIONALLICENCE 700 1- Loucks Lynda Concordia Hip and Knee Institute, 310-1155 Concordia Avenue, R2K 2M9, Winnipeg, MB, Canada aut NATIONALLICENCE 700 1- Khudairy Ammar QEII Health Sciences Centre, Dalhousie University, Halifax, NS, Canada aut NATIONALLICENCE 700 1- Noseworthy Tom Department of Community Health Sciences, University of Calgary, 3rd Floor, TRW Building, 3280 Hospital Drive NW, T2N 4Z6, Calgary, AB, Canada aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/7(2015-07-01), 1775-1784 0962-9343 24:7<1775 2015 24 11136