caa a22 4500 606178708 CHVBK 20210128100758.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s11136-014-0906-2 doi (NATIONALLICENCE)springer-10.1007/s11136-014-0906-2 Valuing EQ-5D health states for Sri Lanka [Elektronische Daten] [Sanjeewa Kularatna, Jennifer Whitty, Newell Johnson, Ruwan Jayasinghe, Paul Scuffham] Purpose: The aim of this study was to derive an algorithm to estimate utility values for the EQ-5D-3L health states based on the preferences of a population sample from Sri Lanka. Methods: The time trade-off method was used to directly value 198 EQ-5D-3L health states in a general population sample (n=780) from Sri Lanka. Stratified cluster sampling with random selection within clusters was used to select the sample from four districts. Each participant valued 15 health states via face-to-face interviews. The best fit model was selected using consistency, parsimony, and goodness of fit. Based on logical inconsistency, numerous sub-samples were also used for model specification. For each model, the numbers of illogical orderings in the resulting value set were also examined. Results: Generalised least squares with random effects were found to be the best specification. The sub-sample consisting of participants with less than seven logical inconsistent observations produced no illogical ordering in the final value set and is considered the preferred model. Compared to value sets in other countries, a high disutility is associated with level 3 deficits in the mobility dimension. More than 50% of health states in the Sri Lankan value set are deemed worse than death health states. Conclusions: Sri Lankan utility values for EQ-5D-3L states deviate markedly from existing values for upper middle and high-income countries. It is important to have country-specific utility values to conduct cost-utility analysis. Springer International Publishing Switzerland, 2014 EQ-5D nationallicence Utility nationallicence Low- and middle-income country nationallicence QALY nationallicence Health state valuation nationallicence Logical inconsistency nationallicence Pairwise interactions nationallicence Kularatna Sanjeewa Centre for Applied Health Economics, School of Medicine, Logan Campus, Griffith University, University Drive, Meadowbrook, 4131, Brisbane, QLD, Australia aut Whitty Jennifer Centre for Applied Health Economics, School of Medicine, Logan Campus, Griffith University, University Drive, Meadowbrook, 4131, Brisbane, QLD, Australia aut Johnson Newell Population and Social Health Research Programme, Griffith Health Institute, Griffith University, Brisbane, QLD, Australia aut Jayasinghe Ruwan Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka aut Scuffham Paul Centre for Applied Health Economics, School of Medicine, Logan Campus, Griffith University, University Drive, Meadowbrook, 4131, Brisbane, QLD, Australia aut Quality of Life Research Springer International Publishing 24/7(2015-07-01), 1785-1793 0962-9343 24:7<1785 2015 24 11136 https://doi.org/10.1007/s11136-014-0906-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0906-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kularatna Sanjeewa Centre for Applied Health Economics, School of Medicine, Logan Campus, Griffith University, University Drive, Meadowbrook, 4131, Brisbane, QLD, Australia aut NATIONALLICENCE 700 1- Whitty Jennifer Centre for Applied Health Economics, School of Medicine, Logan Campus, Griffith University, University Drive, Meadowbrook, 4131, Brisbane, QLD, Australia aut NATIONALLICENCE 700 1- Johnson Newell Population and Social Health Research Programme, Griffith Health Institute, Griffith University, Brisbane, QLD, Australia aut NATIONALLICENCE 700 1- Jayasinghe Ruwan Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka aut NATIONALLICENCE 700 1- Scuffham Paul Centre for Applied Health Economics, School of Medicine, Logan Campus, Griffith University, University Drive, Meadowbrook, 4131, Brisbane, QLD, Australia aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/7(2015-07-01), 1785-1793 0962-9343 24:7<1785 2015 24 11136