caa a22 4500 606178848 CHVBK 20210128100758.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s11136-015-1038-z doi (NATIONALLICENCE)springer-10.1007/s11136-015-1038-z Psychometric properties of the EQ-5D-5L in Thai patients with chronic diseases [Elektronische Daten] [Phantipa Sakthong, Nontapat Sonsa-ardjit, Pattarin Sukarnjanaset, Wipaporn Munpan] Purpose: Due to the problem of high ceiling effects of the EQ-5D-3L, the EQ-5D-5L was developed. However, little was known about the full psychometric properties of the EQ-5D-5L. Thus, this study aimed to evaluate its practicality, reliability, validity, and responsiveness in Thai patients with chronic diseases. Methods: One thousand one hundred and fifty-six adults taking a medicine at least 3months were identified from three university hospitals in Bangkok, Thailand, between July 2014 and March 2015. Practicality was evaluated by administration times and ceiling effects. Test-retest reliability was assessed using weighted kappa and intraclass correlation coefficients (ICCs). Validity was tested with correlations between the EQ-5D-5L and WHOQoL-BREF and SF-12v2, and known-groups validity. Responsiveness was measured with standardized effect sizes (SES). Results: The mean administration time was approximately 2min, and the ceiling effect of the EQ-5D-5L index was 13.6%. The weighted kappa values and ICC of the EQ-5D-5L were 0.48-0.61 and 0.82, respectively. Similar dimensions of the EQ-5D-5L had higher correlations with those of WHOQoL-BREF and SF-12v2. As expected, elderly, female, low-educated, unemployed, higher number of comorbidities and medicines, patients' perception of poor disease control, and having an adverse drug reaction tended to have poorer EQ-5D-5L scores. The SES of EQ-5D-5L index and EQ-VAS were considered small (0.33-0.42) for the improved group. For the worsened group, the SES of the EQ-5D-5L index were considered small (−0.29) but that of the EQ-VAS considered large (−0.82). Conclusions: The EQ-5D-5L was practical, reliable, valid, and responsive in Thai patients with chronic diseases. Springer International Publishing Switzerland, 2015 EQ-5D-5L nationallicence Psychometrics nationallicence Reliability nationallicence Validity nationallicence Responsiveness nationallicence Thailand nationallicence Sakthong Phantipa Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut Sonsa-ardjit Nontapat Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut Sukarnjanaset Pattarin Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut Munpan Wipaporn Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut Quality of Life Research Springer International Publishing 24/12(2015-12-01), 3015-3022 0962-9343 24:12<3015 2015 24 11136 https://doi.org/10.1007/s11136-015-1038-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-1038-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sakthong Phantipa Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut NATIONALLICENCE 700 1- Sonsa-ardjit Nontapat Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut NATIONALLICENCE 700 1- Sukarnjanaset Pattarin Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut NATIONALLICENCE 700 1- Munpan Wipaporn Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/12(2015-12-01), 3015-3022 0962-9343 24:12<3015 2015 24 11136