caa a22 4500 606178910 CHVBK 20210128100758.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s11136-015-1027-2 doi (NATIONALLICENCE)springer-10.1007/s11136-015-1027-2 Long-term health-related quality of life of living kidney donors: a single-center experience [Elektronische Daten] [Christian Benzing, Hans-Michael Hau, Greta Kurtz, Moritz Schmelzle, Hans-Michael Tautenhahn, Mehmet Morgül, Georg Wiltberger, Johannes Broschewitz, Georgi Atanasov, Anette Bachmann, Michael Bartels] Purpose: Over the last few years, the evaluation of the health-related quality of life (HRQoL) of living kidney donors (LKD) has become of particular interest. The present study sought to evaluate the physical and mental HRQoL after kidney removal. The clinical and paraclinical course of these patients was examined, and the impact of preoperative donor evaluation, donor nephrectomy, and surgical recovery was evaluated. These data were compared with reference data of the general population. Methods: Between 1998 and 2010, 72 living kidney donations were performed at our institution. To assess the HRQoL, two questionnaires—the Short Form 36 (SF-36) and a special LKD questionnaire—were sent to all 72 living donors. The records of the follow-up examinations of all 72 donors were retrospectively analyzed in order to assess the clinical and paraclinical data after kidney donation. Results: Out of 72 donors, 55 (76.4%) responded to the questionnaires. There was no change in systolic and diastolic blood pressure during the 7-year follow-up (p>0.05). Mild proteinuria (>150mg/l) was observed in six cases. Kidney donors had a higher HRQoL compared to the general population with mean values of the physical and mental summation scale (PCS and MCS, respectively) being 51.3 (SD=7.6) and 50.6 (SD=8.1). Peri- or postoperative complications were associated with lower values for physical function and physical component summary (PCS) (p<0.05). Discussion: Living donor kidney transplantation appears to be safe for donors. The HRQoL is excellent. To ensure a positive outcome for donors, a good clinical evaluation of potential donors is essential. Springer International Publishing Switzerland, 2015 Living kidney donors transplantation nationallicence Quality of life nationallicence SF-36 nationallicence Proteinuria nationallicence Hypertension nationallicence Benzing Christian Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Hau Hans-Michael Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Kurtz Greta Department of Anesthesiology and Critical Care, Hospital of Mühlacker, Hermann-Hesse-Straße 34, 75417, Mühlacker, Germany aut Schmelzle Moritz Department of General, Visceral and Transplantation Surgery, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany aut Tautenhahn Hans-Michael Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Morgül Mehmet Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Wiltberger Georg Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Broschewitz Johannes Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Atanasov Georgi Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Bachmann Anette Section for Nephrology, Department of Endocrinology and Nephrology, University Hospital of Leipzig, Leipzig, Germany aut Bartels Michael Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut Quality of Life Research Springer International Publishing 24/12(2015-12-01), 2833-2842 0962-9343 24:12<2833 2015 24 11136 https://doi.org/10.1007/s11136-015-1027-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-1027-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Benzing Christian Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Hau Hans-Michael Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Kurtz Greta Department of Anesthesiology and Critical Care, Hospital of Mühlacker, Hermann-Hesse-Straße 34, 75417, Mühlacker, Germany aut NATIONALLICENCE 700 1- Schmelzle Moritz Department of General, Visceral and Transplantation Surgery, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany aut NATIONALLICENCE 700 1- Tautenhahn Hans-Michael Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Morgül Mehmet Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Wiltberger Georg Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Broschewitz Johannes Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Atanasov Georgi Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 700 1- Bachmann Anette Section for Nephrology, Department of Endocrinology and Nephrology, University Hospital of Leipzig, Leipzig, Germany aut NATIONALLICENCE 700 1- Bartels Michael Department of Visceral, Transplantation, Vascular, and Thoracic Surgery, University Hospital of Leipzig, Liebigstraße 20, 04103, Leipzig, Germany aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/12(2015-12-01), 2833-2842 0962-9343 24:12<2833 2015 24 11136