caa a22 4500 606179259 CHVBK 20210128100800.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s11136-014-0829-y doi (NATIONALLICENCE)springer-10.1007/s11136-014-0829-y Taking into account the impact of attrition on the assessment of response shift and true change: a multigroup structural equation modeling approach [Elektronische Daten] [Mathilde Verdam, Frans Oort, Yvette van der Linden, Mirjam Sprangers] Purpose: Missing data due to attrition present a challenge for the assessment and interpretation of change and response shift in HRQL outcomes. The objective was to handle such missingness and to assess response shift and ‘true change' with the use of an attrition-based multigroup structural equation modeling (SEM) approach. Method: Functional limitations and health impairments were measured in 1,157 cancer patients, who were treated with palliative radiotherapy for painful bone metastases, before [time (T) 0], every week after treatment (T1 through T12), and then monthly for up to 2years (T13 through T24). To handle missing data due to attrition, the SEM procedure was extended to a multigroup approach, in which we distinguished three groups: short survival (3-5 measurements), medium survival (6-12 measurements), and long survival (>12 measurements). Results: Attrition after third, sixth, and 13th measurement occasions was 11, 24, and 41%, respectively. Results show that patterns of change in functional limitations and health impairments differ between patients with short, medium, or long survival. Moreover, three response-shift effects were detected: recalibration of ‘pain' and ‘sickness' and reprioritization of ‘physical functioning.' If response-shift effects would not have been taken into account, functional limitations and health impairments would generally be underestimated across measurements. Conclusions: The multigroup SEM approach enables the analysis of data from patients with different patterns of missing data due to attrition. This approach does not only allow for detection of response shift and assessment of true change across measurements, but also allow for detection of differences in response shift and true change across groups of patients with different attrition rates. Springer International Publishing Switzerland, 2014 Structural equation modeling nationallicence Response shift nationallicence Health-related quality of life nationallicence Attrition nationallicence Missing data nationallicence Multigroup nationallicence Verdam Mathilde Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands aut Oort Frans Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands aut van der Linden Yvette Department of Clinical Oncology, Leiden University Medical Centre, Leiden, The Netherlands aut Sprangers Mirjam Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands aut Quality of Life Research Springer International Publishing 24/3(2015-03-01), 541-551 0962-9343 24:3<541 2015 24 11136 https://doi.org/10.1007/s11136-014-0829-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0829-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Verdam Mathilde Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- Oort Frans Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands aut NATIONALLICENCE 700 1- van der Linden Yvette Department of Clinical Oncology, Leiden University Medical Centre, Leiden, The Netherlands aut NATIONALLICENCE 700 1- Sprangers Mirjam Department of Medical Psychology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/3(2015-03-01), 541-551 0962-9343 24:3<541 2015 24 11136