caa a22 4500 606179348 CHVBK 20210128100800.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s11136-015-0992-9 doi (NATIONALLICENCE)springer-10.1007/s11136-015-0992-9 Validation of the PROMIS physical function measures in a diverse US population-based cohort of cancer patients [Elektronische Daten] [Roxanne Jensen, Arnold Potosky, Bryce Reeve, Elizabeth Hahn, David Cella, James Fries, Ashley Smith, Theresa Keegan, Xiao-Cheng Wu, Lisa Paddock, Carol Moinpour] Purpose: To evaluate the validity of the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function measures in a diverse, population-based cancer sample. Methods: Cancer patients 6-13months post-diagnosis (n=4840) were recruited for the Measuring Your Health study. Participants were diagnosed between 2010 and 2013 with non-Hodgkin lymphoma or cancers of the colorectum, lung, breast, uterus, cervix, or prostate. Four PROMIS physical function short forms (4a, 6b, 10a, and 16) were evaluated for validity and reliability across age and race-ethnicity groups. Covariates included gender, marital status, education level, cancer site and stage, comorbidities, and functional status. Results: PROMIS physical function short forms showed high internal consistency (Cronbach's α=0.92-0.96), convergent validity (fatigue, pain interference, FACT physical well-being all r≥0.68), and discriminant validity (unrelated domains all r≤0.3) across survey short forms, age, and race-ethnicity. Known-group differences by demographic, clinical, and functional characteristics performed as hypothesized. Ceiling effects for higher-functioning individuals were identified on most forms. Conclusions: This study provides strong evidence that PROMIS physical function measures are valid and reliable in multiple race-ethnicity and age groups. Researchers selecting specific PROMIS short forms should consider the degree of functional disability in their patient population to ensure that length and content are tailored to limit response burden. Springer International Publishing Switzerland, 2015 Patient-reported outcomes nationallicence Oncology nationallicence Validation studies nationallicence Physical function nationallicence Jensen Roxanne Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street NW, Suite 4100, 20007, Washington, DC, USA aut Potosky Arnold Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street NW, Suite 4100, 20007, Washington, DC, USA aut Reeve Bryce Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA aut Hahn Elizabeth Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut Cella David Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut Fries James Stanford University, Palo Alto, CA, USA aut Smith Ashley Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut Keegan Theresa Cancer Prevention Institute of California, Fremont, CA, USA aut Wu Xiao-Cheng Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA, USA aut Paddock Lisa Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA aut Moinpour Carol Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut Quality of Life Research Springer International Publishing 24/10(2015-10-01), 2333-2344 0962-9343 24:10<2333 2015 24 11136 https://doi.org/10.1007/s11136-015-0992-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-0992-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jensen Roxanne Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street NW, Suite 4100, 20007, Washington, DC, USA aut NATIONALLICENCE 700 1- Potosky Arnold Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street NW, Suite 4100, 20007, Washington, DC, USA aut NATIONALLICENCE 700 1- Reeve Bryce Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA aut NATIONALLICENCE 700 1- Hahn Elizabeth Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut NATIONALLICENCE 700 1- Cella David Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut NATIONALLICENCE 700 1- Fries James Stanford University, Palo Alto, CA, USA aut NATIONALLICENCE 700 1- Smith Ashley Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MD, USA aut NATIONALLICENCE 700 1- Keegan Theresa Cancer Prevention Institute of California, Fremont, CA, USA aut NATIONALLICENCE 700 1- Wu Xiao-Cheng Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA, USA aut NATIONALLICENCE 700 1- Paddock Lisa Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA aut NATIONALLICENCE 700 1- Moinpour Carol Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/10(2015-10-01), 2333-2344 0962-9343 24:10<2333 2015 24 11136