caa a22 4500 60617978X CHVBK 20210128100802.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s11136-014-0838-x doi (NATIONALLICENCE)springer-10.1007/s11136-014-0838-x Measuring changes in health over time using the EQ-5D 3L and 5L: a head-to-head comparison of measurement properties and sensitivity to change in a German inpatient rehabilitation sampl e [Elektronische Daten] [Ines Buchholz, Kirsten Thielker, You-Shan Feng, Peter Kupatz, Thomas Kohlmann] Purpose: To compare measurement properties and sensitivity to change of the standard version of the EQ-5D (3L) with a newly developed 5-level version (5L) in a multicenter sample of German rehabilitation inpatients (n=230). Methods: Rehabilitation patients (n=114 orthopedic, n=54 psychosomatic, n=62 rheumatic) were asked to complete both versions of the EQ-5D and several other questionnaires at the beginning of, the end of and 3month after inpatient rehabilitation. 3L and 5L were compared regarding missing values, ceiling effects, redistribution properties, informativity and sensitivity to change. Results: There were nearly no missing values in both questionnaires. Ceiling effects were 1.6% points to 16.4% points lower on average for the 5L. For psychosomatic patients, ceiling effects for 5L were as high as in the general German population. Absolute informativity (mean 5L: 1.76, 3L: 1.06) and relative informativity (5L: 0.76, 3L: 0.67) were both higher for 5L. 5L could better detect both positive and negative health changes in most dimensions and patient samples. Overall, patients made better use of the response levels of the 5L. Average proportion of inconsistent responses between 3L and 5L was 6.1%. Conclusions: Cross-sectionally and longitudinally, 5L was associated with an improved ability to detect health changes over time, reduced ceiling effects, and improved discriminatory power. Overall, these findings were in line with previous study outcomes, although differing in magnitude. Since the sample size is moderate and generalizability of the reported results is unclear, further comparisons in other patient populations will be informative and should be encouraged. Springer International Publishing Switzerland, 2014 Quality of life nationallicence EQ-5D nationallicence Psychometric comparison nationallicence Head-to-head comparison nationallicence Sensitivity to change nationallicence German inpatient sample nationallicence Buchholz Ines Institute of Community Medicine, University of Greifswald, Greifswald, Germany aut Thielker Kirsten Salzetalklinik, Bad Salzuflen, Germany aut Feng You-Shan Institute of Community Medicine, University of Greifswald, Greifswald, Germany aut Kupatz Peter Moorbad, Bad Doberan, Germany aut Kohlmann Thomas Institute of Community Medicine, University of Greifswald, Greifswald, Germany aut Quality of Life Research Springer International Publishing 24/4(2015-04-01), 829-835 0962-9343 24:4<829 2015 24 11136 https://doi.org/10.1007/s11136-014-0838-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0838-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Buchholz Ines Institute of Community Medicine, University of Greifswald, Greifswald, Germany aut NATIONALLICENCE 700 1- Thielker Kirsten Salzetalklinik, Bad Salzuflen, Germany aut NATIONALLICENCE 700 1- Feng You-Shan Institute of Community Medicine, University of Greifswald, Greifswald, Germany aut NATIONALLICENCE 700 1- Kupatz Peter Moorbad, Bad Doberan, Germany aut NATIONALLICENCE 700 1- Kohlmann Thomas Institute of Community Medicine, University of Greifswald, Greifswald, Germany aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/4(2015-04-01), 829-835 0962-9343 24:4<829 2015 24 11136