caa a22 4500 606179860 CHVBK 20210128100803.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s11136-015-0933-7 doi (NATIONALLICENCE)springer-10.1007/s11136-015-0933-7 Validation of the Malay version of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) in Malaysia [Elektronische Daten] [Thiagarajan Nagammai, Mohamed Mohazmi, Su Liew, Karuthan Chinna, Pauline Lai] Purpose: To assess the validity and reliability of the Malay version of the Quality of Life (QOL) Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) in Malaysia. Methods: The QUALEFFO-41 was translated from English to Malay and administered to 215 post-menopausal osteoporotic women ≥50years who could understand Malay, at baseline and 4weeks. The SF-36 was administered at baseline to assess convergent validity. To assess discriminative validity, patients with and without back pain were recruited. Results: Confirmatory factor analysis showed that the QUALEFFO-41 had five domains. Good internal consistency was seen in all domains (0.752-0.925) except for the social activity domain (0.692). Test-retest reliability showed adequate correlation for all items (0.752-0.964, p<0.001). Patients with back pain had significantly worse QOL compared with those without (back pain=42.2±10.9, no back pain=33.3±8.9; p<0.001). The total QUALEFFO-41 score and the SF-36 physical and mental composite scores were significantly correlated (−0.636 and −0.529, p<0.001, respectively). Conclusions: The Malay version of the QUALEFFO-41 was found to be a reliable and valid instrument to evaluate the QOL of osteoporotic patients in Malaysia. To enable the QUALEFFO-41 to be used in a multiracial population, further studies should look into validating other versions of the QUALEFFO-41 in Malaysia. Springer International Publishing Switzerland, 2015 Malaysia nationallicence Osteoporosis nationallicence Malay nationallicence QUALEFFO-41 nationallicence Quality of life nationallicence Validation nationallicence Nagammai Thiagarajan Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut Mohazmi Mohamed Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut Liew Su Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut Chinna Karuthan Department of Social Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia aut Lai Pauline Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut Quality of Life Research Springer International Publishing 24/8(2015-08-01), 2031-2037 0962-9343 24:8<2031 2015 24 11136 https://doi.org/10.1007/s11136-015-0933-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 brief-communication jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-0933-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nagammai Thiagarajan Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut NATIONALLICENCE 700 1- Mohazmi Mohamed Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut NATIONALLICENCE 700 1- Liew Su Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut NATIONALLICENCE 700 1- Chinna Karuthan Department of Social Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia aut NATIONALLICENCE 700 1- Lai Pauline Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/8(2015-08-01), 2031-2037 0962-9343 24:8<2031 2015 24 11136