caa a22 4500 606180427 CHVBK 20210128100806.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s11136-014-0783-8 doi (NATIONALLICENCE)springer-10.1007/s11136-014-0783-8 Lymphedema Quality of Life Inventory (LyQLI)-Development and investigation of validity and reliability [Elektronische Daten] [Pia Klernäs, Aina Johnsson, Vibeke Horstmann, Linda Kristjanson, Karin Johansson] Purpose: The purpose of this study was to reduce the 188-item Swedish Lymphedema Quality of Life Inventory (SLQOLI) to an abbreviated, clinically useful version (phase 1) and to test it for reliability and validity (phase 2). Methods: In phase 1 correlation analysis, factor analysis, content validity assessment and expert panels were used to reduce the number of items in SLQOLI to 45 items, which was named, Lymphedema Quality of Life Inventory (LyQLI). In phase 2, LyQLI was sent to 200 patients with lymphedema. 126 patients completed the questionnaire twice to determine stability of the instrument over time. SF-36 was sent to the patients once, correlations between the three domains in LyQLI and the two sum scores Physical Health (PCS) and Mental Health (MCS) in SF-36 were used to assess concurrent validity. Results: The 188-item SLQOLI was reduced to 45-item LyQLI. Four domains were reduced to three: physical, psychosocial and practical. Reliability estimates using ICC for the physical and psychosocial domains were 0.88 (p<0.01) and 0.87 (p<0.01), for the practical domain 0.87 (p<0.01). Cronbach's alpha coefficients for the three domains were 0.88, 0.92 and 0.88, respectively. The physical domain correlated highly significantly with PCS, psychosocial highly significantly with MCS and practical equally highly significantly to both PCS and MCS. Using skewness coefficients, small floor effects in the items were found. Conclusion: The shorter LyQLI demonstrated good reliability and validity with potential use to assess quality of life in clinic settings and in further cross-sectional studies of patients with lymphedema. Springer International Publishing Switzerland, 2015 Health-related quality of life nationallicence Lymphedema nationallicence Disease-specific instrument nationallicence Reliability nationallicence Validity nationallicence Klernäs Pia Division of Physiotherapy, Department of Health Science, Lund University, Lund, Sweden aut Johnsson Aina Department of Neurobiology, Care Sciences and Society Division of Social Work, Karolinska Institutet, Stockholm, Sweden aut Horstmann Vibeke Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden aut Kristjanson Linda Swinburne University of Technology, Melbourne, VIC, Australia aut Johansson Karin Division of Physiotherapy, Department of Health Science, Lund University, Lund, Sweden aut Quality of Life Research Springer International Publishing 24/2(2015-02-01), 427-439 0962-9343 24:2<427 2015 24 11136 https://doi.org/10.1007/s11136-014-0783-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-014-0783-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Klernäs Pia Division of Physiotherapy, Department of Health Science, Lund University, Lund, Sweden aut NATIONALLICENCE 700 1- Johnsson Aina Department of Neurobiology, Care Sciences and Society Division of Social Work, Karolinska Institutet, Stockholm, Sweden aut NATIONALLICENCE 700 1- Horstmann Vibeke Department of Health Sciences, Faculty of Medicine, Lund University, Lund, Sweden aut NATIONALLICENCE 700 1- Kristjanson Linda Swinburne University of Technology, Melbourne, VIC, Australia aut NATIONALLICENCE 700 1- Johansson Karin Division of Physiotherapy, Department of Health Science, Lund University, Lund, Sweden aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/2(2015-02-01), 427-439 0962-9343 24:2<427 2015 24 11136