caa a22 4500 606180591 CHVBK 20210128100807.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s11136-015-1010-y doi (NATIONALLICENCE)springer-10.1007/s11136-015-1010-y Reliability and construct validity of PROMIS® measures for patients with heart failure who undergo heart transplant [Elektronische Daten] [Kathryn Flynn, Mary Dew, Li Lin, Maria Fawzy, Felicia Graham, Elizabeth Hahn, Ron Hays, Robert Kormos, Honghu Liu, Mary McNulty, Kevin Weinfurt] Purpose: To evaluate the reliability and construct validity of measures from the Patient-Reported Outcomes Measurement Information System® (PROMIS®) for patients with heart failure before and after heart transplantation. Methods: We assessed reliability of the PROMIS short forms using Cronbach's alpha and the average marginal reliability. To assess the construct validity of PROMIS computerized adaptive tests and short-form measures, we calculated Pearson product moment correlations between PROMIS measures of physical function, fatigue, depression, and social function and existing PRO measures of similar domains (i.e., convergent validity) as well as different domains (i.e., discriminate validity) in patients with heart failure awaiting heart transplant. We evaluated the responsiveness of these measures to change after heart transplant using effect sizes. Results: Forty-eight patients were included in the analyses. Across the many domains examined, correlations between conceptually similar domains were larger than correlations between different domains of health, demonstrating construct validity. Health status improved substantially after heart transplant (standardized effect sizes, 0.63-1.24), demonstrating the responsiveness of the PROMIS measures. Scores from the computerized adaptive tests and the short forms were similar. Conclusions: This study provides evidence for the reliability and construct validity (including responsiveness to change) of four PROMIS domains in patients with heart failure before and after heart transplant. PROMIS measures are a reasonable choice in this context and will facilitate comparisons across studies and health conditions. Springer International Publishing Switzerland, 2015 Congestive heart failure nationallicence Outcomes research nationallicence Patient-reported outcomes nationallicence Flynn Kathryn Center for Patient Care and Outcomes Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA aut Dew Mary Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA aut Lin Li Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut Fawzy Maria Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut Graham Felicia Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut Hahn Elizabeth Department of Medical Social Sciences and Center for Patient-Centered Outcomes, Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut Hays Ron Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA aut Kormos Robert Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA aut Liu Honghu Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA aut McNulty Mary Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA aut Weinfurt Kevin Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut Quality of Life Research Springer International Publishing 24/11(2015-11-01), 2591-2599 0962-9343 24:11<2591 2015 24 11136 https://doi.org/10.1007/s11136-015-1010-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-1010-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Flynn Kathryn Center for Patient Care and Outcomes Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA aut NATIONALLICENCE 700 1- Dew Mary Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA aut NATIONALLICENCE 700 1- Lin Li Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut NATIONALLICENCE 700 1- Fawzy Maria Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut NATIONALLICENCE 700 1- Graham Felicia Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut NATIONALLICENCE 700 1- Hahn Elizabeth Department of Medical Social Sciences and Center for Patient-Centered Outcomes, Northwestern University Feinberg School of Medicine, Chicago, IL, USA aut NATIONALLICENCE 700 1- Hays Ron Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- Kormos Robert Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA aut NATIONALLICENCE 700 1- Liu Honghu Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA aut NATIONALLICENCE 700 1- McNulty Mary Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA aut NATIONALLICENCE 700 1- Weinfurt Kevin Duke Clinical Research Institute, Duke University School of Medicine, Box 17969, 27715, Durham, NC, USA aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/11(2015-11-01), 2591-2599 0962-9343 24:11<2591 2015 24 11136