caa a22 4500 606180621 CHVBK 20210128100807.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s11136-015-1006-7 doi (NATIONALLICENCE)springer-10.1007/s11136-015-1006-7 Chew Boon-How Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia aut Medication adherence on quality of life among adults with type 2 diabetes mellitus: an exploratory analysis on the EDDMQoL study [Elektronische Daten] [Boon-How Chew] Purpose: This study examined the association between medication adherence (MA) and health-related quality of life (HRQoL) among the adult type 2 diabetes mellitus at the primary care level. Methods: In this cross-sectional study, the 8-item Morisky Medication Adherence Scale (MMAS) was the main independent variable and the World Health Organization Quality of Life-Brief the dependent variable. Besides socio-demographic data, diabetes-related distress (DRD) and depression (DS) were included as covariates. Independent association between the MMAS score and HRQoL was done using multiple linear regression. Results: The participants' response rate was 93.1% (700/752). Majorities were female (52.8%), Malay (52.9%) and married (79.1%). The mean (SD) for age and the MMAS score was 56.9 (10.18) and 5.6 (1.42), respectively. MMAS total score correlated significantly with all HRQoL domains: overall QoL (OQoL) (r=0.17), physical QoL (r=0.11), psychological QoL (r=0.10), social relationship QoL (r=0.15) and environmental QoL (EQoL) (r=0.18). After adjustment for covariates (age, gender, ethnicity, religion, education, income, exercise, macrovascular complications, DRD and DS), MA had persistent effects on OQoL (B=0.53, 95% CI 0.012-1.048) and EQoL (B=0.95, 95% CI 0.235-1.667). Conclusion: MA showed prevalent correlation and positive effects on the domains of HRQoL. Despite the small effects of MA on HRQoL, the sheer presence of the independent effects provides healthcare providers good reason for initiative and intervention to improve MA, which would improve quality of life. Springer International Publishing Switzerland, 2015 Medication adherence nationallicence Quality of life nationallicence Type 2 diabetes mellitus nationallicence Primary care nationallicence DDS : The 17-item Diabetes Distress Scale nationallicence DFP : Diabetic foot problems nationallicence DRD : Diabetes-related distress nationallicence DS : Depression nationallicence EQoL : Environment quality of life nationallicence HRQoL : Health-related quality of life nationallicence MA : Medication adherence nationallicence MacroCx : Macrovascular complications nationallicence MicroCx : Microvascular complications nationallicence MMAS : The 8-item Morisky Medication Adherence Scale nationallicence OQoL : Overall quality of life nationallicence PHQ : The 9-item Patient Health Questionnaire nationallicence PQoL : Physical quality of life nationallicence SRQoL : Social relationships quality of life nationallicence T2DM : Type 2 diabetes mellitus nationallicence WHOQOL-BREF : The World Health Organization Quality of Life-Brief nationallicence YQoL : Psychological quality of life nationallicence Quality of Life Research Springer International Publishing 24/11(2015-11-01), 2723-2731 0962-9343 24:11<2723 2015 24 11136 https://doi.org/10.1007/s11136-015-1006-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-1006-7 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Chew Boon-How Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/11(2015-11-01), 2723-2731 0962-9343 24:11<2723 2015 24 11136