caa a22 4500 606180729 CHVBK 20210128100807.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s11136-015-1004-9 doi (NATIONALLICENCE)springer-10.1007/s11136-015-1004-9 Predicting factors of health-related quality of life in octogenarians: a 3-year follow-up longitudinal study [Elektronische Daten] [Assumpta Ferrer, Francesc Formiga, Oriol Cunillera, M. Megido, Xavier Corbella, Jesús Almeda] Purpose: The proportion of very old people is rising, and so, describing their health-related quality of life (HRQoL) is an important point of interest. The aim of this study was to analyse the predictive factors on HRQoL throughout a 3-year follow-up period, in a community-based cohort of octogenarian people. Methods: From 290 subjects aged 85 and over, sociodemographic and geriatric data, including levels of frailty phenotype assessment, and HRQoL using the EuroQol 5D3L (EQ-5D) instrument were collected. A longitudinal analysis was performed by generalized estimating equations (jointly testing the bivariate effect of variables and its time dependence) and regression mixed models to evaluate the adjusted effect of variables on HRQoL after a 3-year follow-up. Results: In the EQ-5D baseline assessment, the average visual analogue self-rating scale value was 63.82 (SD±19.45), the EQ-5D index was 0.67 (0.34) and the most significant issues were pain/discomfort (61.2%), depression (45.3%) and mobility (44.6%). The third year index was 0.55 (0.38). Independent predictive factors of a lower HRQoL identified by the regression mixed models were female gender (marginal effect ME=−0.101; p=0.003), being pre-frail (ME=−0.142; p=0.011) or frail (ME=−0.071; p=0.030), having heart failure (ME=−0.081; p=0.037) and having a high social risk score (ME=−0.020; p=0.015). In contrast, higher functional status (ME=0.050; p<0.001) and nutritional score (ME=0.013; p=0.011) appeared to be predictive factors of an enhanced HRQoL. The adjusted effect of "time of follow-up” had no statistical significance. Conclusion: Frail individuals at baseline have a significant lower HRQoL, whereas a higher functional status and nutritional status are independent predicting factors of an enhanced HRQoL after 3years of follow-up. These findings may encourage clinicians in order to asses HRQoL. Springer International Publishing Switzerland, 2015 Health-related quality of life nationallicence Frailty nationallicence Disability nationallicence Age 80 and older nationallicence Ferrer Assumpta Primary Healthcare Centre ‘El Plà' CAP-I, CAP - El Plà, Pl. Felip Alcantara s/n, 08980, Sant Feliu de Llobregat, Barcelona, Spain aut Formiga Francesc Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, Barcelona, Spain aut Cunillera Oriol Primary Health Care Research Institute (IDIAP) Jordi Gol, ICS, Barcelona, Spain aut Megido M. Primary Health Care Research Institute (IDIAP) Jordi Gol, ICS, Barcelona, Spain aut Corbella Xavier Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, Barcelona, Spain aut Almeda Jesús Primary Health Care Research Institute (IDIAP) Jordi Gol, ICS, Barcelona, Spain aut Quality of Life Research Springer International Publishing 24/11(2015-11-01), 2701-2711 0962-9343 24:11<2701 2015 24 11136 https://doi.org/10.1007/s11136-015-1004-9 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s11136-015-1004-9 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ferrer Assumpta Primary Healthcare Centre ‘El Plà' CAP-I, CAP - El Plà, Pl. Felip Alcantara s/n, 08980, Sant Feliu de Llobregat, Barcelona, Spain aut NATIONALLICENCE 700 1- Formiga Francesc Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, Barcelona, Spain aut NATIONALLICENCE 700 1- Cunillera Oriol Primary Health Care Research Institute (IDIAP) Jordi Gol, ICS, Barcelona, Spain aut NATIONALLICENCE 700 1- Megido M. Primary Health Care Research Institute (IDIAP) Jordi Gol, ICS, Barcelona, Spain aut NATIONALLICENCE 700 1- Corbella Xavier Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, Barcelona, Spain aut NATIONALLICENCE 700 1- Almeda Jesús Primary Health Care Research Institute (IDIAP) Jordi Gol, ICS, Barcelona, Spain aut NATIONALLICENCE 773 0- Quality of Life Research Springer International Publishing 24/11(2015-11-01), 2701-2711 0962-9343 24:11<2701 2015 24 11136