caa a22 4500 606182241 CHVBK 20210128100815.0 cr unu---uuuuu 210128e20150301xx s 000 0 eng 10.1007/s10876-015-0855-0 doi (NATIONALLICENCE)springer-10.1007/s10876-015-0855-0 Syntheses, Structures and Antioxidant Activities of Fullerenols: Knowledge Learned at the Atomistic Level [Elektronische Daten] [Zhenzhen Wang, Shukuang Wang, Zhanghui Lu, Xingfa Gao] Fullerenol nanoparticles have intriguing potentials in biomedical applications. However, the structures, mechanisms of syntheses and mechanisms of antioxidant activities of fullerenols at the atomistic level, which substantialize their properties and applications, remain opened questions. Here, we review the syntheses, structures and antioxidant activities of fullerenols. Especially, we focus on the knowledge at the atomistic level. Experimentally, fullerenols can be synthesized using oxidation reactions in either acidic conditions or alkaline conditions. The latter reactions yield fullerenols with high hydroxyl numbers and better water solubility. For fullerenol structures, a precision structural model has been recently proposed for C60 fullerenols, which explain the experimentally-observed radical anion properties and pH-dependent infrared spectroscopic properties. Calculations have suggested that the most thermodynamically stable structures of many fullerenols have hydroxyls located aggregately in islands on the fullerene cages, although the most stable configuration of C60(OH)24 has hydroxyls distributed on C60 equator. Two different ·OH-scavenging mechanisms are possible for fullerenols. Fullerenols with low degrees of hydroxylation prefer the ·OH addition mechanism, whereas those with high degrees of hydroxylation prefer the hydrogen abstraction mechanism. The O 2 ∙− -scavenging mechanism is related to redox potentials, charges and H-bond nets of the fullerenols. Springer Science+Business Media New York, 2015 Fullerenols nationallicence Synthesis nationallicence Structure nationallicence Reaction mechanism nationallicence Antioxidant activity nationallicence Wang Zhenzhen Jiangxi Inorganic Membrane Materials Engineering Research Centre, College of Chemistry and Chemical Engineering, Jiangxi Normal University, 330022, Nanchang, China aut Wang Shukuang Department of Physics, Ocean University of China, 266100, Qingdao, China aut Lu Zhanghui Jiangxi Inorganic Membrane Materials Engineering Research Centre, College of Chemistry and Chemical Engineering, Jiangxi Normal University, 330022, Nanchang, China aut Gao Xingfa CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, 100049, Beijing, China aut Journal of Cluster Science Springer US; http://www.springer-ny.com 26/2(2015-03-01), 375-388 1040-7278 26:2<375 2015 26 10876 https://doi.org/10.1007/s10876-015-0855-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10876-015-0855-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Zhenzhen Jiangxi Inorganic Membrane Materials Engineering Research Centre, College of Chemistry and Chemical Engineering, Jiangxi Normal University, 330022, Nanchang, China aut NATIONALLICENCE 700 1- Wang Shukuang Department of Physics, Ocean University of China, 266100, Qingdao, China aut NATIONALLICENCE 700 1- Lu Zhanghui Jiangxi Inorganic Membrane Materials Engineering Research Centre, College of Chemistry and Chemical Engineering, Jiangxi Normal University, 330022, Nanchang, China aut NATIONALLICENCE 700 1- Gao Xingfa CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, 100049, Beijing, China aut NATIONALLICENCE 773 0- Journal of Cluster Science Springer US; http://www.springer-ny.com 26/2(2015-03-01), 375-388 1040-7278 26:2<375 2015 26 10876