caa a22 4500 606182543 CHVBK 20210128100816.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s00405-014-3054-y doi (NATIONALLICENCE)springer-10.1007/s00405-014-3054-y Clinical outcomes and quality of life in patients with nasal polyposis after functional endoscopic sinus surgery [Elektronische Daten] [Vojko Djukic, Zoran Dudvarski, Nenad Arsovic, Milovan Dimitrijevic, Ljiljana Janosevic] The majority of studies have shown that the use of functional endoscopic sinus surgery (FESS) leads to symptomatic improvement in 73-98.4% of patients with chronic rhinosinusitis and nasal polyposis (NP). The aim of the study is to evaluate clinical outcomes and quality of life (QoL) in patients with NP after FESS. The prospective study included 85 consecutive adult patients (≥18years) with NP who were operated on using FESS after failure of the medicamentous treatment and in certain cases of surgical treatment. QoL was assessed by Short Form-36 Health Survey (SF-36) questionnaire, and the symptom intensity was presented using visual analogue scale (VAS). The objective finding was presented as endoscopic and computerized tomography (CT) score. The intensity of each symptom, the values of symptom scores (major, minor and total), the values of dimension scales and summary scales of the QoL, as well as the values of endoscopic score through three periods of time (pre-surgery, 6 and 12months after the surgery) were analyzed. Following the FESS, mean intensity values of all individual symptoms and symptom scores were significantly lower and the values of all dimension scales and summary scales of QoL were significantly higher (p<0.05). There was no statistically significant difference in symptom intensity and QoL after 6 and 12months of surgical treatment (p>0.05). Endoscopic score was on average significantly lower after 6 and 12months of FESS (p<0.05), but the mean score value after 12months of operation was significantly higher in relation to that after 6months of surgery (p<0.05). Nevertheless, the recurrence of NP was observed in 28 patients (32.9%) in the follow-up period. In conclusion, FESS in NP patients results in significant improvement of symptom intensity, QoL and endoscopic score. While the intensity of symptoms and QoL showed a tendency to maintain between 6 and 12 months after surgery, endoscopic score showed a tendency of exacerbation in the same period. Springer-Verlag Berlin Heidelberg, 2014 Nasal polyposis nationallicence Quality of life nationallicence Functional endoscopic sinus surgery nationallicence Outcomes nationallicence Djukic Vojko Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut Dudvarski Zoran Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut Arsovic Nenad Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut Dimitrijevic Milovan Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut Janosevic Ljiljana Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/1(2015-01-01), 83-89 0937-4477 272:1<83 2015 272 405 https://doi.org/10.1007/s00405-014-3054-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3054-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Djukic Vojko Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut NATIONALLICENCE 700 1- Dudvarski Zoran Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut NATIONALLICENCE 700 1- Arsovic Nenad Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut NATIONALLICENCE 700 1- Dimitrijevic Milovan Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut NATIONALLICENCE 700 1- Janosevic Ljiljana Faculty of Medicine, University of Belgrade, Belgrade, Serbia aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/1(2015-01-01), 83-89 0937-4477 272:1<83 2015 272 405