caa a22 4500 606182853 CHVBK 20210128100818.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00405-014-3068-5 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3068-5 Re-operative thyroid surgery: a 20-year prospective cohort study at a tertiary referral centre [Elektronische Daten] [John. Hardman, J. Smith, P. Nankivell, N. Sharma, J. Watkinson] Re-operative thyroid surgery is a relatively uncommon procedure complicated by distorted anatomy and post-operative tissue changes. Surgery may follow initial benign or malignant pathology. Published outcomes vary widely in the literature. This study aims to report our outcomes from re-operative thyroid surgery. Patient demographics and complication rates for consecutive thyroidectomies performed by a single surgeon at a tertiary centre were collected between 1993 and 2013. Outcomes in re-operative surgery are analysed and compared with local and national data. Cases of re-operative surgery following benign disease are further analysed for histology, re-presenting symptoms and time between procedures. Our cohort comprised 1,657 cases including 164 re-operative procedures (101 malignant, 63 benign). Within our cohort re-operative cases were on average 4years older (mean 49.9 vs 45.9years, p=0.001) and had a higher incidence of haematoma formation (4.3 vs 1.7%, p=0.033) and transient recurrent laryngeal nerve palsy (5.5 vs 2.5%, p=0.044) compared to primary surgery. Rates of permanent hypocalcaemia (2.4 vs 1.8%, p=0.540) and permanent RLN palsy (1.8 vs 0.4%, p=0.051) were higher in the re-operative group but did not reach significance. Comparison of complications following re-operation for benign and malignant disease revealed no significant differences. Mean interval to re-operation for benign cases was 17.4years with 74.6% found to have multinodular goitre at repeat procedure. Re-operative procedures comprised around 10% of thyroid surgery at our centre. Re-operative cases experienced more complications than primary surgery but permanent rates were low. Re-operative surgery may therefore be safely considered in experienced hands. Springer-Verlag Berlin Heidelberg, 2014 Thyroidectomy nationallicence Reoperation nationallicence Complications nationallicence Revalidation nationallicence Benign nationallicence Hardman John Department of Otolaryngology Head and Neck Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut Smith J. Department of Otolaryngology Head and Neck Surgery, University Hospital of North Staffordshire, Princes Road, ST4 7LN, Stoke-on-Trent, Staffordshire, UK aut Nankivell P. Department of Otolaryngology Head and Neck Surgery, Heartlands Hospital, Bordesley Green East, B9 5SS, Birmingham, UK aut Sharma N. Department of Otolaryngology Head and Neck Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut Watkinson J. Department of Otolaryngology Head and Neck Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/6(2015-06-01), 1503-1508 0937-4477 272:6<1503 2015 272 405 https://doi.org/10.1007/s00405-014-3068-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3068-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hardman John Department of Otolaryngology Head and Neck Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 700 1- Smith J. Department of Otolaryngology Head and Neck Surgery, University Hospital of North Staffordshire, Princes Road, ST4 7LN, Stoke-on-Trent, Staffordshire, UK aut NATIONALLICENCE 700 1- Nankivell P. Department of Otolaryngology Head and Neck Surgery, Heartlands Hospital, Bordesley Green East, B9 5SS, Birmingham, UK aut NATIONALLICENCE 700 1- Sharma N. Department of Otolaryngology Head and Neck Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 700 1- Watkinson J. Department of Otolaryngology Head and Neck Surgery, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/6(2015-06-01), 1503-1508 0937-4477 272:6<1503 2015 272 405