caa a22 4500 606182896 CHVBK 20210128100818.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00405-014-3076-5 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3076-5 Correlation between the severity of apnea and hypopnea sleep, hypertension and serum lipid and glycemic: a case control study [Elektronische Daten] [Celio de Sousa Rodrigues, Amanda Lira] The purpose of this study was to evaluate the correlation between the severity of obstructive sleep apnea (OSA) and the levels of blood pressure (BP), lipids and glucose, as intermittent hypoxia increases BP, changes the oxidative balance, and can induce the formation of free radicals and atherogenesis. 32 patients were evaluated about BP during wakefulness and sleep, total cholesterol and lipids, LDL (low-density lipoprotein), HDL (high-density lipoprotein), triglycerides, glucose and polysomnography. They were divided into four groups according to the respiratory events per hour of sleep (RDI): control group (RDI<5), Group I (RDI 5-15), Group II (RDI 15-30), Group III (RDI>30). There was no increase in BP in groups' cases, the verification of systolic (p=0.429) and diastolic (p=0.475) BP in 24h, systolic (p=0.277) and diastolic (p=0.143) BP during wakefulness, and systolic (p=0.394) and diastolic (p=0.703) BP during sleep in the control group. When implementing the Spearman correlation test, a correlation directly proportional to the severity of the disease was not observed. Regarding the level of serum total cholesterol (p=0.092), LDL (p=0.242), HDL (p=0.517), triglycerides (p=0.947), total lipids (p=0.602) and glucose (0.355), there was no statistically significant difference between groups (p>0.05 for all parameters). There is no correlation between the severity of OSA and BP levels in 24h, during daytime, during the sleep and serum levels of LDL and HDL cholesterol. The Author(s), 2014 Obstructive sleep apnea nationallicence Hypertension nationallicence Dyslipidemia nationallicence Hyperglycemia nationallicence de Sousa Rodrigues Celio Federal University of Alagoas, Maceió, Brazil aut Lira Amanda Department of Otorhinolaryngology, Santa Casa Hospital of Alagoas, Maceió, Brazil aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/6(2015-06-01), 1509-1515 0937-4477 272:6<1509 2015 272 405 https://doi.org/10.1007/s00405-014-3076-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3076-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de Sousa Rodrigues Celio Federal University of Alagoas, Maceió, Brazil aut NATIONALLICENCE 700 1- Lira Amanda Department of Otorhinolaryngology, Santa Casa Hospital of Alagoas, Maceió, Brazil aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/6(2015-06-01), 1509-1515 0937-4477 272:6<1509 2015 272 405