caa a22 4500 606182993 CHVBK 20210128100819.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s00405-014-3082-7 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3082-7 The effect of radiotherapy on mucociliary clearance in patients with laryngeal and nasopharyngeal cancer [Elektronische Daten] [Caner Kılıç, Ümit Tunçel, Ela Cömert, Bektaş Kaya] The present study aimed to demonstrate how the nasal mucociliary transport times are affected in the patients receiving radiotherapy for head-neck tumor in two different anatomic localizations. The study included 44 patients receiving radiotherapy under the diagnoses of the nasopharyngeal and laryngeal cancer. The mucociliary transport times of both groups were measured via saccharine tablets before radiotherapy, and at months 3 and 6 after radiotherapy. The difference between the groups was statistically evaluated. The pre-irradiation (pre-RT) mean transport times of NPC and LC patients were 9.7 and 9.1min, respectively. The difference in the mucociliary transport times between these two groups was not statistically significant (p=0.49). The mean transport time was 26.1min at post-RT month 3, 23.9min, at month 6; the change from pre-RT to month 3 was significant (p<0.05) and the change from month 3 to 6 was not statistically significant (p=0.182). The mean transport time of the LC patients was 16.8min. At post-RT month 3, 12.4min. at month 6; the change from pre-RT to month 3 (p<0.05) and the change from month 3 to 6 were statistically significant (p=0.007). It was found that radiotherapy affected the physiological conditions of the patients with nasopharyngeal cancer in a more severe and sustained way compared to the LC patients, which negatively affects the patient's response to the treatment by the resulting organic and psychological effects. Springer-Verlag Berlin Heidelberg, 2014 Larynx nationallicence Nasopharynx nationallicence Mucociliary clearance nationallicence Radiotherapy nationallicence Kılıç Caner Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut Tunçel Ümit Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut Cömert Ela Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut Kaya Bektaş Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/6(2015-06-01), 1517-1520 0937-4477 272:6<1517 2015 272 405 https://doi.org/10.1007/s00405-014-3082-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3082-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kılıç Caner Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut NATIONALLICENCE 700 1- Tunçel Ümit Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut NATIONALLICENCE 700 1- Cömert Ela Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut NATIONALLICENCE 700 1- Kaya Bektaş Department of Otorhinolaryngology, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Mehmet Akif Ersoy District 13. St. No: 56, Yenimahalle, 06200, Ankara, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/6(2015-06-01), 1517-1520 0937-4477 272:6<1517 2015 272 405