caa a22 4500 606183248 CHVBK 20210128100820.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-015-3629-2 doi (NATIONALLICENCE)springer-10.1007/s00405-015-3629-2 CO2 laser cordectomy for T1-T2 glottic cancer: oncological and functional long-term results [Elektronische Daten] [Giulia Bertino, Giulia Degiorgi, Carmine Tinelli, Salvatore Cacciola, Antonio Occhini, Marco Benazzo] The purpose of this study was to assess the validity of CO2 laser cordectomy in the treatment of early glottic cancer and to determine the impact of margin status on disease-free survival and of the operation on voice quality. This is a retrospective review of 169 patients. Quantitative and qualitative variables were statistically compared. The impact on overall and disease-free survivals of different variables was calculated by univariate and multivariate analyses. Ten-year overall and disease free-survivals were 75%and 60%, respectively. Age and clinical stage showed a significant negative impact on overall survival, while margin status both on overall and disease-free survivals. The degree of dysphonia was directly related to the extension of the resection. This series confirms the good oncologic and functional outcomes of laser surgery for Tis, T1 and selected T2 glottic tumors. Patients with positive margins should undergo a further treatment or a very close follow-up. Springer-Verlag Berlin Heidelberg, 2015 Larynx nationallicence Early glottic cancer nationallicence Laser cordectomy nationallicence Surgical margins nationallicence Voice preservation nationallicence Bertino Giulia Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut Degiorgi Giulia Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut Tinelli Carmine Biometric Unit, IRCCS Policlinico S. Matteo Foundation, P.le Golgi 2, 27100, Pavia, Italy aut Cacciola Salvatore Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut Occhini Antonio Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut Benazzo Marco Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2389-2395 0937-4477 272:9<2389 2015 272 405 https://doi.org/10.1007/s00405-015-3629-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-015-3629-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bertino Giulia Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Degiorgi Giulia Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Tinelli Carmine Biometric Unit, IRCCS Policlinico S. Matteo Foundation, P.le Golgi 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Cacciola Salvatore Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Occhini Antonio Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut NATIONALLICENCE 700 1- Benazzo Marco Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Policlinico S. Matteo Foundation, University of Pavia, P.le Golgi 2, 27100, Pavia, Italy aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2389-2395 0937-4477 272:9<2389 2015 272 405