caa a22 4500 606183310 CHVBK 20210128100820.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-014-3219-8 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3219-8 Analgesic effect of magnesium in post-tonsillectomy patients: a prospective randomised clinical trial [Elektronische Daten] [S. Tugrul, N. Degirmenci, S. Eren, R. Dogan, B. Veyseller, O. Ozturan] The aim of this study was to assess the analgesic, bleeding and nausea/vomiting effects of magnesium with and without metamizol on post-tonsillectomy patients. This prospective and randomised clinical trial included 54 patients aged 18-63 years who were scheduled for elective tonsillectomy. The patients were randomly divided into two groups and administered either magnesium with metamizol or only metamizol. They had been classified as physical status class I and II using the American Society of Anesthesiologists guidelines. All patients underwent the same surgical procedure performed by a single surgeon. The groups did not differ according to age, sex, or duration of anaesthesia or surgery. Postoperative pain, bleeding and nausea/vomiting were evaluated using the VAS and bleeding and nausea/vomiting scores on the first, fifth and tenth days. On the first, fifth and tenth postoperative days, the VAS scores of the magnesium with metamizol group were significantly lower than those of the metamizol-only group (p1=0.001; p5=0.015; p10=0.015). There were no significant differences in postoperative bleeding and nausea/vomiting scores between the two groups (p=0.425 and p=0.258, respectively). This study showed that magnesium enhanced the analgesic effect on post-tonsillectomy pain. Use of magnesium with an analgesic drug may be beneficial for management of post-tonsillectomy pain . Springer-Verlag Berlin Heidelberg, 2014 Post-tonsillectomy pain nationallicence Magnesium nationallicence Tonsillectomy nationallicence Pain nationallicence Tugrul S. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut Degirmenci N. Department of Otorhinolaryngology and Head and Neck Surgery, Artvin State Hospital, Artvin, Turkey aut Eren S. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut Dogan R. Department of Otorhinolaryngology and Head and Neck Surgery, Bayrampasa State Hospital, Istanbul, Turkey aut Veyseller B. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut Ozturan O. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2483-2487 0937-4477 272:9<2483 2015 272 405 https://doi.org/10.1007/s00405-014-3219-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3219-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Tugrul S. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Degirmenci N. Department of Otorhinolaryngology and Head and Neck Surgery, Artvin State Hospital, Artvin, Turkey aut NATIONALLICENCE 700 1- Eren S. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Dogan R. Department of Otorhinolaryngology and Head and Neck Surgery, Bayrampasa State Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Veyseller B. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Ozturan O. Medical Faculty, Department of Otorhinolaryngology and Head and Neck Surgery, Bezmialem Vakif University, Istanbul, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2483-2487 0937-4477 272:9<2483 2015 272 405