caa a22 4500 606183418 CHVBK 20210128100821.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-014-3189-x doi (NATIONALLICENCE)springer-10.1007/s00405-014-3189-x ‘What will I be like' after my diagnosis of head and neck cancer? [Elektronische Daten] [S. Rogers, E. Hogg, W. Cheung, L. Lai, P. Jassal, D. Lowe, A. Kanatas] Consequences of treating head and neck cancer are reflected in health-related quality of life (HRQOL) patient-reported outcomes. HRQOL is an important outcome alongside survival and recurrence. However, relatively little HRQOL information is in a format that patients and oncology teams can easily interpret as a guide to likely outcomes following curative treatment. The study aim was to collate University of Washington Quality of Life (UW-QOL) questionnaires collected 1995-2012 at the Regional Head and Neck Surgical Unit with a view of summarizing key clinical-demographic influences on HRQOL outcomes at 2years following diagnosis. Patients completing UW-QOL questionnaires at 9-60months had their record closest to 2years selected for cross-sectional analyses, while all questionnaires were analyzed to assess temporal trends. 65% (1,134) of survivors to 9months had a UW-QOL record in the cross-sectional analysis (median 23months). Overall 1,349 completed 5,573 UW-QOL questionnaires. Various associations were seen, notably late overall clinical staging and treatment adversely associated with UW-QOL physical functioning domains. Logistic regression was used to better understand the predictive factors of UW-QOL outcome and determined the final formatting of tables for results. These tables provide important reference data about UW-QOL outcome at 2years relevant to patients at the outset of their cancer journey. The increasing amount of HRQOL data allows for quite detailed subgroup analysis, which can help give patients and the clinical team a better understanding of likely long-term HRQOL outcomes. How this is best utilized in clinical care needs further evaluation. Springer-Verlag Berlin Heidelberg, 2014 Quality of life nationallicence Health-related quality of life nationallicence Head and neck cancer nationallicence UW-QOL nationallicence Patient-reported outcomes nationallicence Expectations nationallicence Rogers S. Evidence-Based Practice Research Centre (EPRC), Faculty of Health and Social Care, Edge Hill University, St Helens Road, L39 4QP, Ormskirk, UK aut Hogg E. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut Cheung W. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut Lai L. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut Jassal P. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut Lowe D. Evidence-Based Practice Research Centre (EPRC), Faculty of Health and Social Care, Edge Hill University, St Helens Road, L39 4QP, Ormskirk, UK aut Kanatas A. Leeds Teaching Hospitals and St James Institute of Oncology, Leeds, UK aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2463-2472 0937-4477 272:9<2463 2015 272 405 https://doi.org/10.1007/s00405-014-3189-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3189-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rogers S. Evidence-Based Practice Research Centre (EPRC), Faculty of Health and Social Care, Edge Hill University, St Helens Road, L39 4QP, Ormskirk, UK aut NATIONALLICENCE 700 1- Hogg E. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut NATIONALLICENCE 700 1- Cheung W. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut NATIONALLICENCE 700 1- Lai L. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut NATIONALLICENCE 700 1- Jassal P. Faculty of Medicine, Liverpool University, L69 3BX, Liverpool, UK aut NATIONALLICENCE 700 1- Lowe D. Evidence-Based Practice Research Centre (EPRC), Faculty of Health and Social Care, Edge Hill University, St Helens Road, L39 4QP, Ormskirk, UK aut NATIONALLICENCE 700 1- Kanatas A. Leeds Teaching Hospitals and St James Institute of Oncology, Leeds, UK aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2463-2472 0937-4477 272:9<2463 2015 272 405