caa a22 4500 606183469 CHVBK 20210128100821.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-015-3633-6 doi (NATIONALLICENCE)springer-10.1007/s00405-015-3633-6 Diagnosis and management with botulinum toxin in 11 cases of laryngeal synkinesis [Elektronische Daten] [Asier Lekue, Isabel García-López, Susana Santiago, Antonio Del Palacio, Javier Gavilán] Laryngeal synkinesis is a vocal fold movement disorder produced by a misdirected reinnervation after a recurrent laryngeal nerve injury. Its symptoms differ greatly between patients, requiring diverse therapeutical approaches. We aim to describe our experience in the diagnosis and treatment of different laryngeal synkinesis presentations. 11 patients diagnosed between 2011 and 2014 in a tertiary referral center with laryngeal synkinesis confirmed by laryngeal electromyography were included in our study. All medical records and laryngoscopic and electromyographic data were reviewed retrospectively. Four patients had previous unilateral vocal fold palsy and seven had a bilateral palsy with different degrees of clinical involvement. All of them showed paradoxical movements during inhalation in videofibrolaryngoscopic examination. Laryngeal electromyography confirmed the diagnosis of laryngeal synkinesis. Dyspnea was the main presentation symptom. Three patients with mild symptoms were not treated. Patients with unilateral vocal fold immobility were successfully treated with periodic botulinum toxin injections. Patients with bilateral immobility had a good initial response to botulinum toxin, although in some of them, a posterior cordectomy had to be finally performed. In conclusion, laryngeal synkinesis is a heterogeneous clinic entity that appears in patients with unilateral or bilateral vocal fold paralysis. Videofibrolaryngoscopy and laryngeal electromyography are essential to a correct diagnosis. Botulinum toxin injections are the main treatment for symptomatic cases, even if in bilateral palsy cases more aggressive treatments are often required. Springer-Verlag Berlin Heidelberg, 2015 Laryngeal synkinesis nationallicence Synkinesis nationallicence Laryngeal electromyography nationallicence Botulinum toxin nationallicence Vocal fold paralysis nationallicence Lekue Asier Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut García-López Isabel Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut Santiago Susana Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut Del Palacio Antonio Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut Gavilán Javier Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2397-2402 0937-4477 272:9<2397 2015 272 405 https://doi.org/10.1007/s00405-015-3633-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-015-3633-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lekue Asier Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut NATIONALLICENCE 700 1- García-López Isabel Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut NATIONALLICENCE 700 1- Santiago Susana Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut NATIONALLICENCE 700 1- Del Palacio Antonio Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut NATIONALLICENCE 700 1- Gavilán Javier Department of Otolaryngology, La Paz University Hospital, Paseo de la Castellana 261, 28046, Madrid, Spain aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2397-2402 0937-4477 272:9<2397 2015 272 405