caa a22 4500 606183558 CHVBK 20210128100822.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-015-3559-z doi (NATIONALLICENCE)springer-10.1007/s00405-015-3559-z Drug-induced sleep endoscopy and simulated snoring in patients with sleep-disordered breathing: agreement of anatomic changes in the upper airway [Elektronische Daten] [Michael Herzog, Patrick Kellner, Sebastian Plößl, Alexander Glien, Christian Rohrmeier, Thomas Kühnel, Stefan Plontke, Beatrice Herzog] Drug-induced sleep endoscopy (DISE) and simulated snoring (SimS) are performed as part of the diagnostic procedure in patients with suspected sleep-disordered breathing (SDB). Despite both techniques frequently performed, they have rarely been evaluated yet in terms of agreement of the obtained results. Both diagnostic procedures were performed consecutively in 40 patients with SDB and documented identically. The obtained data were analysed with respect to the agreement of both procedure at different levels of the oropharynx as well as different patterns of obstruction and vibration. The anterior-posterior collapsibility of the soft palate/uvula revealed a moderate agreement between SimS and DISE (κ=0.42; 95% CI 0.22-0.63). The dorsal shift of the tongue base agreed moderate for patients with an AHI below 10 (κ=0.47) and above 25 (κ=0.44) between SimS ad DISE. The lateral and circular pharyngeal collapsibility at velum and tongue base level did not agree between SimS and DISE, was higher for DISE and could be partially reversed by mandibular protrusion. Collapse patterns of the soft palate and uvula can be induced by SimS and resemble the patterns induced by DISE. The dorsalization of the tongue base can be simulated to a lower extent by SimS. Lateral and circular patterns of collapse at the upper and lower oropharynx induced by DISE do not seem to be simulated by SimS. SimS seems to be an additional method to screen the collapsibility of the soft palate and uvula prior to DISE. Springer-Verlag Berlin Heidelberg, 2015 Simulated snoring nationallicence SimS nationallicence Drug-induced sleep endoscopy nationallicence DISE nationallicence AHI nationallicence Disoprivan nationallicence Herzog Michael Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut Kellner Patrick Department of Anaesthesiology, University Medical Center Schleswig-Holstein, Ratzeburger Allee 16, 23538, Lübeck, Germany aut Plößl Sebastian Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut Glien Alexander Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut Rohrmeier Christian Department of Otorhinolaryngology, Head and Neck Surgery, Franz-Joseph-Strauß-Allee 11, 93053, Regensburg, Germany aut Kühnel Thomas Department of Otorhinolaryngology, Head and Neck Surgery, Franz-Joseph-Strauß-Allee 11, 93053, Regensburg, Germany aut Plontke Stefan Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut Herzog Beatrice Institute of Medical Epidemiology Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 8, 06112, Halle (Saale), Germany aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2541-2550 0937-4477 272:9<2541 2015 272 405 https://doi.org/10.1007/s00405-015-3559-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-015-3559-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Herzog Michael Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut NATIONALLICENCE 700 1- Kellner Patrick Department of Anaesthesiology, University Medical Center Schleswig-Holstein, Ratzeburger Allee 16, 23538, Lübeck, Germany aut NATIONALLICENCE 700 1- Plößl Sebastian Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut NATIONALLICENCE 700 1- Glien Alexander Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut NATIONALLICENCE 700 1- Rohrmeier Christian Department of Otorhinolaryngology, Head and Neck Surgery, Franz-Joseph-Strauß-Allee 11, 93053, Regensburg, Germany aut NATIONALLICENCE 700 1- Kühnel Thomas Department of Otorhinolaryngology, Head and Neck Surgery, Franz-Joseph-Strauß-Allee 11, 93053, Regensburg, Germany aut NATIONALLICENCE 700 1- Plontke Stefan Department of Otorhinolaryngology, Head and Neck Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 01620, Halle (Saale), Germany aut NATIONALLICENCE 700 1- Herzog Beatrice Institute of Medical Epidemiology Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 8, 06112, Halle (Saale), Germany aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2541-2550 0937-4477 272:9<2541 2015 272 405