caa a22 4500 60618368X CHVBK 20210128100822.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-014-3297-7 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3297-7 Extranodal sinonasal Rosai-Dorfman disease: a clinical study of 10 cases [Elektronische Daten] [Hong-Gang Duan, Chun-Quan Zheng, De-Hui Wang, Guo-Qiang Ding, Ji-Qin Luo, Chao-Ping Zang, Chang Yu] Sinonasal Rosai-Dorfman disease (S-RDD) is a rare form of RDD limited to the sinonasal cavity. Multipatient studies of Chinese S-RDD and documentation of its clinical spectrum are rare. This study aimed to identify the clinical profiles of Chinese S-RDD. Medical records of and tissue sections from 10 patients diagnosed with S-RDD between 2007 and 2014 were reviewed. Data on clinical presentations, endoscopy signs, imageological change, treatment and outcome were analyzed. The mean age of five male and five female patients at the first visit was 40.3years and the mean follow-up period was 58.6months. Based on the lesion sites, five cases were divided into an anterior sinonasal group, accompanied by symptoms of epistaxis, nasal obstruction and nasal dorsal deformity. Five other cases were divided into a posterior sinonasal group, accompanied by symptoms of hyposmia, epistaxis and nasal obstruction. Endoscopy signs and imageological changes in the anterior group showed diffuse infiltration of the RDD lesion under the septum mucosa, but in the posterior group the RDD lesions often showed as formations on polyps. At the end of follow-up, only one case spontaneously resolved without surgery; two cases in the anterior sinonasal group and three cases in the posterior sinonasal group recurred after endoscopic surgery, but surgery can result in short-term symptomatic control and restoration of function in all cases. S-RDD of the anterior and posterior sinonasal cavity may have different clinical characteristics; endoscopic surgery is effective for short-term symptomatic control and restoration of function for S-RDD. Springer-Verlag Berlin Heidelberg, 2014 Rosai-Dorfman disease nationallicence Sinonasaldisease nationallicence Endoscopic surgery nationallicence Duan Hong-Gang Department of Otolaryngology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China aut Zheng Chun-Quan Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut Wang De-Hui Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut Ding Guo-Qiang Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut Luo Ji-Qin Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut Zang Chao-Ping Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut Yu Chang Department of Pathology, Zhejiang Cancer Hospital, Hangzhou, China aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2313-2318 0937-4477 272:9<2313 2015 272 405 https://doi.org/10.1007/s00405-014-3297-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3297-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Duan Hong-Gang Department of Otolaryngology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China aut NATIONALLICENCE 700 1- Zheng Chun-Quan Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Wang De-Hui Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Ding Guo-Qiang Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Luo Ji-Qin Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Zang Chao-Ping Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Yu Chang Department of Pathology, Zhejiang Cancer Hospital, Hangzhou, China aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2313-2318 0937-4477 272:9<2313 2015 272 405