caa a22 4500 60618371X CHVBK 20210128100822.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-014-3175-3 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3175-3 Low bone mineral density and vitamin D deficiency in patients with benign positional paroxysmal vertigo [Elektronische Daten] [Hossam Talaat, Ghada Abuhadied, Ahmed Talaat, Mohamed Abdelaal] Several studies indicated the association between benign paroxysmal positional vertigo (BPPV) with osteoporosis and vitamin D deficiency implying that abnormal calcium metabolism may underlie BPPV. The aim of the present study is to confirm the correlation between BPPV and both decrease in bone mineral density (BMD) and vitamin D deficiency. The study group included 80 patients with idiopathic BPPV (52 females, 28 males), with age range 31-71years (47.6±9.1). The patients were divided into two groups; recurrent BPPV group including 36 subjects and non-recurrent group including 44 subjects. The control group included 100 healthy volunteers with age and gender distribution similar to the study group. All the subjects in the study were examined using Dual-energy X-ray absorptiometry to assess BMD, and serum 25-hydroxyvitamin D for vitamin D assessment. The accepted normal levels were T-score>−1, and 25-hydroxyvitamin D>30ng/ml. Twenty-six (26%) subjects showed abnormal T-score in the control group; 26 (59%) in the non-recurrent BPPV and 22 (61%) in the recurrent BPPV group. Chi square test showed significant difference between the control group and both BPPV groups. The control group had significantly higher 25-hydroxyvitamin D levels than the BPPV subgroups (p<0.05). Moreover, the 25-hydroxyvitamin D was significantly lower in the recurrent BPPV than it was in the non-recurrent subgroup (p<0.05). The results of the current study associate between reduced BMD and development/recurrence of BPPV. Moreover, low levels of vitamin D were related to development of BPPV while very low levels were associated with recurrence of BPPV. The co-occurrence of two morbidities is not by itself supportive of a relationship, but the cumulating studies correlating between BPPV and both vitamin D deficiency and low BMD indicate the investigation and treatment of those disorders in cases with recurrent BPPV. Springer-Verlag Berlin Heidelberg, 2014 Otoconia nationallicence Osteopenia nationallicence Osteoporosis nationallicence Recurrence of BPPV nationallicence Vitamin D nationallicence Bone marrow density nationallicence Talaat Hossam Audiology Unit, ENT Department, Menoufiya University, Shibin al-Kawm, Egypt aut Abuhadied Ghada Audiology Unit, ENT Department, Bani Sweef University, Bani Sweif, Egypt aut Talaat Ahmed Internal Medicine Department, Suez Canal University, Ismaïlia, Egypt aut Abdelaal Mohamed Radiology Department, Hadiclinic Hospital, Kuwait City, Kuwait aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2249-2253 0937-4477 272:9<2249 2015 272 405 https://doi.org/10.1007/s00405-014-3175-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3175-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Talaat Hossam Audiology Unit, ENT Department, Menoufiya University, Shibin al-Kawm, Egypt aut NATIONALLICENCE 700 1- Abuhadied Ghada Audiology Unit, ENT Department, Bani Sweef University, Bani Sweif, Egypt aut NATIONALLICENCE 700 1- Talaat Ahmed Internal Medicine Department, Suez Canal University, Ismaïlia, Egypt aut NATIONALLICENCE 700 1- Abdelaal Mohamed Radiology Department, Hadiclinic Hospital, Kuwait City, Kuwait aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2249-2253 0937-4477 272:9<2249 2015 272 405