caa a22 4500 606183787 CHVBK 20210128100823.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00405-014-3186-0 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3186-0 Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature [Elektronische Daten] [Malene Rokkjaer, Tejs Klug] Unsuspected tonsillar malignancy in routine tonsillectomy specimens is rare. A potentially increased risk of unsuspected tonsillar malignancy in adult patients presenting with peritonsillar abscess (PTA) was noted in a recent review. Furthermore, a literature search revealed several case reports concerning tonsillar malignancy presenting as PTA. Thus, the aim of the current study was to explore the prevalence of tonsillar malignancy in adult patients with PTA. A retrospective review of all adult patients undergoing tonsillectomy due to PTA from January 2001 to December 2012 at the Ear-Nose-Throat Department was performed. In 275 consecutive adult patients with PTA (median age 40years, range 30-89years), we identified one patient with unsuspected tonsillar malignancy (prevalence 0.3%); a 40-year-old, previously healthy, male was diagnosed with acute myeloid leukaemia. Reviewing the literature, we identified 13 cases of tonsillar malignancy presenting as PTA (median age 49years, range 2-66years). Our data represents the only series of histological examined tonsillectomy specimens from PTA patients reported in the literature. We identified one case of unsuspected tonsillar malignancy in this relatively small series. We find it important to stress, that we had no knowledge of this patient before designing the study. Hence, the prevalence of 0.3% is unbiased in this respect. More, and preferably, larger studies are needed to determine the prevalence with greater certainty. At present, no definitive conclusions can be made, but clinicians should be aware that PTA infrequently masquerade tonsillar malignancy. Springer-Verlag Berlin Heidelberg, 2014 Tonsillectomy nationallicence Peritonsillar abscess nationallicence Risk factors nationallicence Histology nationallicence Pathology nationallicence Malignancy nationallicence Rokkjaer Malene Department of Otorhinolaryngology, Head and Neck Surgery, Holstebro Hospital, Laegårdvej 12, 7500, Holstebro, Denmark aut Klug Tejs Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus, Denmark aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2439-2444 0937-4477 272:9<2439 2015 272 405 https://doi.org/10.1007/s00405-014-3186-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3186-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Rokkjaer Malene Department of Otorhinolaryngology, Head and Neck Surgery, Holstebro Hospital, Laegårdvej 12, 7500, Holstebro, Denmark aut NATIONALLICENCE 700 1- Klug Tejs Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Noerrebrogade 44, 8000, Aarhus, Denmark aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/9(2015-09-01), 2439-2444 0937-4477 272:9<2439 2015 272 405