caa a22 4500 606183841 CHVBK 20210128100823.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00405-014-2948-z doi (NATIONALLICENCE)springer-10.1007/s00405-014-2948-z Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: a prospective controlled study [Elektronische Daten] [M. Pezzoli, M. Magnano, L. Maffi, L. Pezzoli, P. Marcato, M. Orione, D. Cupi, G. Bongioannini] The most commonly used treatment for sensorineural sudden hearing loss (SSHL) in clinical practice is the administration of steroids; however, a favorable result is not always obtained. We studied 58 patients who failed to recover after primary treatment with IV steroids, 44 of these met our inclusion criteria (mean age 50.7, 27 males, range 30-74). We treated 23 patients (mean age 47.3, 16 males, age range 22-74) with hyperbaric oxygen therapy (HBO) (2.5 ATA for 60min for 15 treatments), while 21 (mean age 54.5, 11 males, age range 22-71) patients refused to be treated and served as a non-randomized control group. Patients treated with HBO had a mean improvement of 15.6dB (SD±15.3), with 1 of them completely healed, 5 with a good recovery, 10 with a fair recovery and 7 unchanged. Patients who were not treated had a spontaneous mean improvement of 5.0dB (SD±11.4) with 3 patients with a good recovery, 1 patient with a fair recovery and 17 patients unchanged. Mean improvement was significantly better in patients treated with HBO compared to controls (p=0.0133). Patients with worst hearing had the greater degree of improvement whether or not they were treated in the first 10days after the onset of the hearing loss or between 11 and 30days. In conclusion, hyperbaric oxygen therapy can lead to significant improvement of pure tone hearing thresholds in patients with SSHL who failed primary corticosteroid treatment and are within 4weeks of the onset of deafness. Springer-Verlag Berlin Heidelberg, 2014 Sudden deafness nationallicence Sudden sensorineural hearing loss nationallicence Hyperbaric oxygen treatment nationallicence Salvage treatment nationallicence Pezzoli M. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut Magnano M. ENT Department, Hospital "E Agnelli”, Pinerolo, Italy aut Maffi L. Centro di Ossigenoterapia Iperbarica OTIP, Via Pola 33, Turin, Italy aut Pezzoli L. London, UK aut Marcato P. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut Orione M. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut Cupi D. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut Bongioannini G. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/7(2015-07-01), 1659-1666 0937-4477 272:7<1659 2015 272 405 https://doi.org/10.1007/s00405-014-2948-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-2948-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pezzoli M. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Magnano M. ENT Department, Hospital "E Agnelli”, Pinerolo, Italy aut NATIONALLICENCE 700 1- Maffi L. Centro di Ossigenoterapia Iperbarica OTIP, Via Pola 33, Turin, Italy aut NATIONALLICENCE 700 1- Pezzoli L. London, UK aut NATIONALLICENCE 700 1- Marcato P. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Orione M. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Cupi D. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut NATIONALLICENCE 700 1- Bongioannini G. ENT Department, Hospital Mauriziano "Umberto I”, Corso Re Umberto 109, 10128, Turin, Italy aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/7(2015-07-01), 1659-1666 0937-4477 272:7<1659 2015 272 405