caa a22 4500 606183868 CHVBK 20210128100823.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00405-015-3505-0 doi (NATIONALLICENCE)springer-10.1007/s00405-015-3505-0 Audiological changes over time in adolescents and young adults with auditory neuropathy spectrum disorder [Elektronische Daten] [Hunsur Chandan, Prashanth Prabhu] Auditory neuropathy spectrum disorder (ANSD) describes a condition in which a patient's otoacoustic emissions (OAE) are (or were at one time) present and auditory brainstem responses (ABR) are abnormal or absent. ANSD is also diagnosed based on the presence of cochlear microphonics and abnormal or absent ABRs with or without abnormalities of OAE. We noted the changes in audiological characteristics over time with respect to pure tone thresholds, OAEs and Speech Identification Scores (SIS) in seven individuals with ANSD. The results indicated that all the individuals with ANSD had decreased SIS over time, whereas there was subsequent reduction in pure tone thresholds only in nine out of fourteen ears. There was absence of OAEs for two individuals in both ears during the follow-up evaluations. There was no regular pattern of changes in pure tone thresholds or SIS across all individuals. This indicates that there may be gradual worsening of hearing abilities in individuals with ANSD. Thus, regular follow-up and monitoring of audiological changes are necessary for individuals with ANSD. Also, longitudinal studies need to be done to further add evidence to the audiological changes over time in individuals with ANSD. Springer-Verlag Berlin Heidelberg, 2015 Auditory neuropathy spectrum disorder nationallicence Pure tone thresholds nationallicence Otoacoustic emissions nationallicence Speech Identification Scores nationallicence Chandan Hunsur Department of Speech Language and Hearing Science, College of Health and Human Science, Purdue University, West Lafayette, USA aut Prabhu Prashanth Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Naimisham Campus, 570006, Mysore, Karnataka, India aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/7(2015-07-01), 1801-1807 0937-4477 272:7<1801 2015 272 405 https://doi.org/10.1007/s00405-015-3505-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-015-3505-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chandan Hunsur Department of Speech Language and Hearing Science, College of Health and Human Science, Purdue University, West Lafayette, USA aut NATIONALLICENCE 700 1- Prabhu Prashanth Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Naimisham Campus, 570006, Mysore, Karnataka, India aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/7(2015-07-01), 1801-1807 0937-4477 272:7<1801 2015 272 405