caa a22 4500 606183884 CHVBK 20210128100823.0 cr unu---uuuuu 210128e20150701xx s 000 0 eng 10.1007/s00405-014-3241-x doi (NATIONALLICENCE)springer-10.1007/s00405-014-3241-x Objective assessment of persistent rhinitis in Chinese and its relationship with serum indicators [Elektronische Daten] [Ke-Jia Cheng, Shen-Qing Wang, Shan Lin, Shui-Hong Zhou] Persistent rhinitis (PR) is a chronic disease that affects millions of people. However, it lacks of a useful method, which can indicate the actual severity of the inflammation in PR patients. This study was designed to seek an examination which could reflect the actual severity of PR disease. The serum Phadiatop test, ECP level, four-phase rhinomanometry, and acoustic rhinometry were assessed in 91 adult patients with PR and 10 healthy controls. The serum total IgE was determined in some of the patients and all of the controls. The patients were divided into four groups: ARWO, ARWTO, NARWO and NARWTO. 40% (22/55) of AR and 33.3% (13/36) of NAR patients never complained of persistent nasal obstruction. Serum ECP levels were increased in the ARWO group. Serum total IgE was significantly elevated in the AR groups. MCA1-Min and MCA1-T were significantly reduced in the ARWO, ARWTO, and NARWO groups. NV6-Min and NV6-T were decreased in all PR groups, but only some of these differences were significant. In the ARWO group, MCA2-Min (r=−0.252), MCA2-T (r=−0.377), NV6-Min (r=−0.32), and NV6-T (r=−0.311) had significant relationships with serum ECP. We recommend acoustic rhinometry as a useful routine tool for the diagnosis of PR, even among patients without persistent subjective nasal obstruction. This technique might reveal the actual status of nasal congestion. An elevated serum ECP level might indicate severe AR and is negatively correlated with the results of acoustic rhinometry. Springer-Verlag Berlin Heidelberg, 2014 Allergic rhinitis nationallicence Nonallergic rhinitis nationallicence Eosinophil cationic protein nationallicence Acoustic rhinometry nationallicence Rhinomanometry nationallicence Cheng Ke-Jia Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut Wang Shen-Qing Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut Lin Shan Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut Zhou Shui-Hong Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/7(2015-07-01), 1679-1685 0937-4477 272:7<1679 2015 272 405 https://doi.org/10.1007/s00405-014-3241-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3241-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cheng Ke-Jia Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut NATIONALLICENCE 700 1- Wang Shen-Qing Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut NATIONALLICENCE 700 1- Lin Shan Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut NATIONALLICENCE 700 1- Zhou Shui-Hong Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, 310003, Hangzhou, Zhejiang Province, People's Republic of China aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/7(2015-07-01), 1679-1685 0937-4477 272:7<1679 2015 272 405