caa a22 4500 606184325 CHVBK 20210128100825.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s00405-014-3428-1 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3428-1 Endolymphatic sac surgery versus tenotomy of the stapedius and tensor tympani muscles in the management of patients with unilateral definite Meniere's disease [Elektronische Daten] [Silviu Albu, Gregorio Babighian, Maurizio Amadori, Franco Trabalzini] This study aims to compare the outcomes of patients with Meniere's disease submitted to either endolymphatic mastoid shunt (ES) or tenotomy of the stapedius and tensor tympani muscles (TSTM). This is a retrospective chart review of patients treated with ES or TSTM between 2000 and 2010 and followed up for at least 12months. The main outcomes were represented by: (1) vertigo class, hearing stage and functional level according to the American Academy of Otolaryngology-Head and Neck Surgery criteria; (2) adjustment of dizziness handicap inventory (DHI) and (3) complete and substantial vertigo control using the Kaplan-Meier survival method. Sixty-three patients met the inclusion criteria: 34 underwent ES and 29 TSTM. The baseline demographic characteristics, the hearing stage, the functional level, the DHI and hearing levels were not different between the two groups. No significant difference in vertigo class was demonstrated: 66% of TSTM patients attained class A compared to 44% in the ES group (p=0.14). Kaplan-Meier survival curves specific to class A showed significant differences, favoring TSTM (log-rank test, p=0.022). TSTM patients demonstrated significantly improved functional level (p=0.0004) and improved DHI scores (p=0.001). Eight ES patients (25%) demanded a second surgical attempt compared to none in the TSTM. Aural fullness was significantly improved in TSTM group (p=0.01), while the difference in tinnitus improvement was non-significant. Hearing preservation was significantly better in TSTM group (p=0.001). TSTM is a safe surgical procedure, with significant vertigo control rates, and important hearing preservation rates. More patients and longer follow-up are needed to support our preliminary findings. Springer-Verlag Berlin Heidelberg, 2014 Meniere's disease nationallicence Endolymphatic mastoid shunt nationallicence Tenotomy of the stapedius nationallicence Tensor tympani muscles nationallicence Vertigo control nationallicence Survival curves nationallicence Albu Silviu II-nd Department of Otolaryngology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Str. Republicii nr. 18, 400015, Cluj-Napoca, Romania aut Babighian Gregorio Operative Unit of Otolaryngology and Otosurgery, Padua University, Padua, Italy aut Amadori Maurizio Otology Department, Hospital Dolo-Mirano, Veneto, Italy aut Trabalzini Franco Otology and Skull Base Surgery Unit, Siena University Hospital, Siena, Italy aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/12(2015-12-01), 3645-3650 0937-4477 272:12<3645 2015 272 405 https://doi.org/10.1007/s00405-014-3428-1 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3428-1 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Albu Silviu II-nd Department of Otolaryngology, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Str. Republicii nr. 18, 400015, Cluj-Napoca, Romania aut NATIONALLICENCE 700 1- Babighian Gregorio Operative Unit of Otolaryngology and Otosurgery, Padua University, Padua, Italy aut NATIONALLICENCE 700 1- Amadori Maurizio Otology Department, Hospital Dolo-Mirano, Veneto, Italy aut NATIONALLICENCE 700 1- Trabalzini Franco Otology and Skull Base Surgery Unit, Siena University Hospital, Siena, Italy aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/12(2015-12-01), 3645-3650 0937-4477 272:12<3645 2015 272 405