caa a22 4500 606184449 CHVBK 20210128100826.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s00405-015-3502-3 doi (NATIONALLICENCE)springer-10.1007/s00405-015-3502-3 Long-term efficacy of Nd:YAG laser photocoagulation vs. liquid paraffin plus antiseptic cream in the treatment of recurrent epistaxis [Elektronische Daten] [Jing Zhang, Rongxing Qiu, Chunsheng Wei] The objective of this study was to evaluate the long-term efficacy of Nd:YAG laser photocoagulation with that of liquid paraffin plus antiseptic cream in the management of recurrent epistaxis. Eighty consecutive patients who suffered from recurrent anterior epistaxis presented to the Otolaryngology Department at the Eye and ENT Hospital, Fudan University between February 2011 and June 2011. These patients with histories of recurrent epistaxis were randomly assigned to receive treatment in an outpatient setting consisting of either a combination of liquid paraffin plus antiseptic cream (Group 1) or Nd:YAG laser photocoagulation (Group 2). Main outcome measures: the following outcome measures were assessed: bleeding intensity; bleeding frequency 2years after treatment (0=no bleeding, 1=reduced bleeding, 2=the same, 3=worse), participant's perception of discomfort during the management (grade 0-10, where 10 is the worst pain), and complications. Finally, 70 patients remain in our study. At 2years, 86% of laser patients versus 31% of control patients had no reported bleeding. The outcome score at 2years after treatment showed a significant difference between the two groups (P=0.000, P<0.01). The median and mean±SD pain levels experienced were 5.0 and 5.2±2.2. Both groups had no complications. It can be further concluded that Nd:YAG laser photocoagulation is a preferable therapy in the treatment of recurrent epistaxis in long-term efficacy. The level of pain associated with the procedure was well tolerated. It is a simple, easy, safe and rapid therapy, which can be performed in an office setting. Springer-Verlag Berlin Heidelberg, 2015 Epistaxis nationallicence Nd:YAG laser nationallicence Liquid paraffin nationallicence Antiseptic cream nationallicence Photocoagulation nationallicence Zhang Jing Department of Otolaryngology and Laser Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, 200031, Shanghai, China aut Qiu Rongxing Department of Otolaryngology and Laser Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, 200031, Shanghai, China aut Wei Chunsheng Department of Otolaryngology and Laser Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, 200031, Shanghai, China aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/12(2015-12-01), 3721-3725 0937-4477 272:12<3721 2015 272 405 https://doi.org/10.1007/s00405-015-3502-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-015-3502-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zhang Jing Department of Otolaryngology and Laser Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Qiu Rongxing Department of Otolaryngology and Laser Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, 200031, Shanghai, China aut NATIONALLICENCE 700 1- Wei Chunsheng Department of Otolaryngology and Laser Surgery, Eye, Ear, Nose and Throat Hospital, Fudan University, 200031, Shanghai, China aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/12(2015-12-01), 3721-3725 0937-4477 272:12<3721 2015 272 405