caa a22 4500 606184465 CHVBK 20210128100826.0 cr unu---uuuuu 210128e20151201xx s 000 0 eng 10.1007/s00405-014-3422-7 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3422-7 Correlation between hippocampal sulcus width and severity of obstructive sleep apnea syndrome [Elektronische Daten] [Galip Akhan, Murat Songu, Sibel Ayik, Canan Altay, Serdar Kalemci] The aim of the present study was to evaluate the relationship between obstructive sleep apnea syndrome (OSAS) severity and the hippocampal sulcus width in a cohort of subjects with OSAS and controls. A total of 149 OSAS patients and 60 nonapneic controls were included in the study. Overnight polysomnograpy was performed in all patients. Hippocampal sulcus width of the patients was measured by a radiologist blinded to the diagnosis of the patients. Other variables noted for each patient were as follows: gender, age, body mass index, apnea hypopnea index, Epworth sleepiness scale, sleep efficacy, mean saturation, lowest O2 saturation, longest apnea duration, neck circumference, waist circumference, hip circumference. A total of 149 OSAS patients were divided into three groups: mild OSAS (n=54), moderate OSAS (n=40), severe OSAS (n=55) groups. The control group consisted of patients with AHI <5 (n=60). Hippocampal sulcus width was 1.6±0.83mm in the control group; while 1.9±0.81mm in mild OSAS, 2.1±0.60mm in moderate OSAS, and 2.9±0.58mm in severe OSAS groups (p<0.001). Correlation analysis of variables revealed that apnea hypopnea index (rs=0.483, p<0.001) was positively correlated with hippocampal sulcus width. Our findings demonstrated that severity of OSAS might be associated with various pathologic mechanisms including increased hippocampal sulcus width. Springer-Verlag Berlin Heidelberg, 2014 Hippocampal sulcus width nationallicence Obstructive sleep apnea nationallicence Akhan Galip Faculty of Medicine, Department of Neurology, Izmir Katip Celebi University, Izmir, Turkey aut Songu Murat Department of Otorhinolaryngology, Ataturk Training and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey aut Ayik Sibel Faculty of Medicine, Department of Chest Diseases, Izmir Katip Celebi University, Izmir, Turkey aut Altay Canan Faculty of Medicine, Department of Radiology, Dokuz Eylul University, Izmir, Turkey aut Kalemci Serdar Faculty of Medicine, Department of Chest Diseases, Mugla University, Mugla, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/12(2015-12-01), 3763-3768 0937-4477 272:12<3763 2015 272 405 https://doi.org/10.1007/s00405-014-3422-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3422-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akhan Galip Faculty of Medicine, Department of Neurology, Izmir Katip Celebi University, Izmir, Turkey aut NATIONALLICENCE 700 1- Songu Murat Department of Otorhinolaryngology, Ataturk Training and Research Hospital, Izmir Katip Celebi University, Izmir, Turkey aut NATIONALLICENCE 700 1- Ayik Sibel Faculty of Medicine, Department of Chest Diseases, Izmir Katip Celebi University, Izmir, Turkey aut NATIONALLICENCE 700 1- Altay Canan Faculty of Medicine, Department of Radiology, Dokuz Eylul University, Izmir, Turkey aut NATIONALLICENCE 700 1- Kalemci Serdar Faculty of Medicine, Department of Chest Diseases, Mugla University, Mugla, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/12(2015-12-01), 3763-3768 0937-4477 272:12<3763 2015 272 405