caa a22 4500 606184988 CHVBK 20210128100829.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00405-014-3231-z doi (NATIONALLICENCE)springer-10.1007/s00405-014-3231-z Effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation [Elektronische Daten] [Ali Eftekharian, Maryam Amizadeh, Kamran Mottaghi, Farhad Safari, Mozhgan Mahani, Leila Ranjbar, Ali Abdi, Nooshin Mokari] The purpose of the present study was to evaluate effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation. A prospective clinical study in a single-subject design was conducted in the cochlear implant center of a tertiary care University-based hospital. Sixty-one cochlear-implanted children with bilateral, severe to profound sensory neural hearing loss were enrolled in the study. During the operation electrically evoked compound action potentials (e-ECAP) were measured in two phase of general anesthesia; in deep and in light anesthesia. Thresholds of e-ECAP in these two phases of anesthesia were compared. Thirty-one children received HiRes90k1j prosthesis and 30 children received CI24RE prosthesis. Thresholds difference of electrically evoked compound action potential between light and deep anesthesia in all tested electrodes in either group were statistically significant (P<0.001). Non-measurable e-ECAP in some electrodes at deep anesthesia was measurable in light phase of anesthesia. Depth of anesthesia can have significant influence on e-ECAP threshold and it is important to reduce the depth of anesthesia to achieve better results. Springer-Verlag Berlin Heidelberg, 2014 Cochlear implant nationallicence General anesthesia nationallicence Depth of anesthesia nationallicence Electrically evoked compound action potential nationallicence Auditory evoked compound action potential nationallicence Eftekharian Ali Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran aut Amizadeh Maryam Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran aut Mottaghi Kamran Department of Anesthesia, Shahid-Beheshti University of medical sciences, Tehran, Iran aut Safari Farhad Department of Anesthesia, Shahid-Beheshti University of medical sciences, Tehran, Iran aut Mahani Mozhgan Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran aut Ranjbar Leila Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran aut Abdi Ali Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran aut Mokari Nooshin Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 2697-2701 0937-4477 272:10<2697 2015 272 405 https://doi.org/10.1007/s00405-014-3231-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3231-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Eftekharian Ali Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran aut NATIONALLICENCE 700 1- Amizadeh Maryam Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran aut NATIONALLICENCE 700 1- Mottaghi Kamran Department of Anesthesia, Shahid-Beheshti University of medical sciences, Tehran, Iran aut NATIONALLICENCE 700 1- Safari Farhad Department of Anesthesia, Shahid-Beheshti University of medical sciences, Tehran, Iran aut NATIONALLICENCE 700 1- Mahani Mozhgan Department of Otorhinolaryngology, Loghman Hospital, Shahid-Beheshti University of medical sciences, Kamali Ave. Kargar, 13336-31151, Tehran, Iran aut NATIONALLICENCE 700 1- Ranjbar Leila Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran aut NATIONALLICENCE 700 1- Abdi Ali Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran aut NATIONALLICENCE 700 1- Mokari Nooshin Department of Audiology, Shahid-Beheshti University of medical sciences, Tehran, Iran aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 2697-2701 0937-4477 272:10<2697 2015 272 405