caa a22 4500 606185151 CHVBK 20210128100830.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00405-014-3410-y doi (NATIONALLICENCE)springer-10.1007/s00405-014-3410-y A randomized study of temperature-controlled versus bipolar radiofrequency for inferior turbinate reduction [Elektronische Daten] [Wish Banhiran, Paraya Assanasen, Pongsakorn Tantilipikorn, Nongyoa Nujchanart, Siriporn Voraprayoon, Chaweewan Bunnag] The objective of this study is to compare outcomes of temperature-controlled radiofrequency (TCRF) and bipolar radiofrequency (BRF) for inferior turbinate reduction in patients with chronic rhinitis (CR). This was a prospective, randomized non-inferiority trial. Eighty-four adult patients with CR refractory to medication were randomized into two intervention groups: TCRF(42) or BRF(42). Primary outcomes consisted of patient-orientated visual analog scale (VAS; 0-10) of nasal obstruction at 4th postoperative week. Secondary subjective outcomes included VAS of nasal discharge, sneezing, hyposmia, and postnasal drip. Objective outcomes included crusting, mucociliary transportation time, minimal cross-sectional area, total nasal volume, and nasal airway resistance performed by blind assessors before and at 4th postoperative week and 1-year follow-up. Baseline and perioperative data showed no statistically significant difference between both groups, except for longer operative time in TCRF (481.5±36.2 vs. 37.1±3.0s, p<0.001) and slightly more crusts in BRF group (p=0.04). Both intention-to-treat and per-protocol analyses, TCRF(39) versus BRF(41), revealed no significant difference among subjective and objective outcomes between two groups at 4th postoperative week. The 95% confidence intervals of mean differences of VAS scores of all subjective symptoms were within defined margin (−1.5 to 1.5), except for nasal discharge. At 1-year follow-up, there was still no significant difference in the outcomes. Minimal pain and minor bleeding without serious adverse effects from both interventions were reported. Both BRF and TCRF resulted in similar short-term outcomes, while less operative time was found in BRF group. Further studies, particularly, on cost-effectiveness should be conducted for better treatment selection. Level of evidence: 1b. Springer-Verlag Berlin Heidelberg, 2014 Radiofrequency nationallicence Temperature controlled nationallicence Bipolar nationallicence Inferior turbinate reduction nationallicence Chronic rhinitis nationallicence Thai nationallicence Banhiran Wish Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut Assanasen Paraya Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut Tantilipikorn Pongsakorn Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut Nujchanart Nongyoa Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut Voraprayoon Siriporn Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut Bunnag Chaweewan Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 2877-2884 0937-4477 272:10<2877 2015 272 405 https://doi.org/10.1007/s00405-014-3410-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3410-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Banhiran Wish Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut NATIONALLICENCE 700 1- Assanasen Paraya Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut NATIONALLICENCE 700 1- Tantilipikorn Pongsakorn Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut NATIONALLICENCE 700 1- Nujchanart Nongyoa Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut NATIONALLICENCE 700 1- Voraprayoon Siriporn Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut NATIONALLICENCE 700 1- Bunnag Chaweewan Department of Oto-Rhino-Laryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, 10700, Bangkok, Thailand aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 2877-2884 0937-4477 272:10<2877 2015 272 405