caa a22 4500 606185259 CHVBK 20210128100830.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00405-014-3256-3 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3256-3 Efficiency of three-dimensional Doppler ultrasonography in assessing nodal metastasis of head and neck cancer [Elektronische Daten] [San-Fu Hong, Yu-Shih Lai, Kwo-Whei Lee, Mu-Kuan Chen] Abstract : The aim of this study was to assess the clinical usefulness of three-dimensional (3D) color Doppler ultrasonography with a novel predictive model in the detection of cervical metastasis of untreated head and neck squamous cell carcinoma patients. We assessed cervical lymph node metastasis in 52 head and neck squamous cell carcinoma patients by 3D color Doppler ultrasonography, magnetic resonance imaging, and [18F] fluorodeoxyglucose positron emission tomography with computed tomography. Pathologic analysis was used as the gold standard for evaluation of these imaging modalities. The rate of correct N staging was 84.6% on ultrasonography, 55.8% on magnetic resonance imaging, and 71.2% on positron emission tomography/computed tomography. On a level-by-level basis, the ultrasonography had 78.9% sensitivity, 99.0% specificity, 93.8% positive predictive value, 96.0% negative predictive value, and 95.7% accuracy. It also showed the highest agreement to histology results as compared with magnetic resonance imaging and positron emission tomography/computed tomography (kappa value=0.832, 0.506, and 0.537, respectively). 3D Doppler ultrasonography with our prediction model provides a rapid, low-cost, noninvasive, and reliable method with low inter-observation variations for detecting neck metastasis of head and neck squamous cell carcinoma patients. Springer-Verlag Berlin Heidelberg, 2014 Three-dimensional Doppler ultrasonography prediction model nationallicence Initial staging of untreated head and neck cancer nationallicence Metastatic cervical lymph nodes nationallicence Hong San-Fu Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua City, Changhua County, Taiwan aut Lai Yu-Shih Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua City, Changhua County, Taiwan aut Lee Kwo-Whei Department of Medical Image, Changhua Christian Hospital, Changhua, Taiwan aut Chen Mu-Kuan Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua City, Changhua County, Taiwan aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 2985-2991 0937-4477 272:10<2985 2015 272 405 https://doi.org/10.1007/s00405-014-3256-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3256-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hong San-Fu Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua City, Changhua County, Taiwan aut NATIONALLICENCE 700 1- Lai Yu-Shih Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua City, Changhua County, Taiwan aut NATIONALLICENCE 700 1- Lee Kwo-Whei Department of Medical Image, Changhua Christian Hospital, Changhua, Taiwan aut NATIONALLICENCE 700 1- Chen Mu-Kuan Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, 500, Changhua City, Changhua County, Taiwan aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 2985-2991 0937-4477 272:10<2985 2015 272 405