caa a22 4500 606185496 CHVBK 20210128100832.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1007/s00405-014-3306-x doi (NATIONALLICENCE)springer-10.1007/s00405-014-3306-x Hypopharyngeal reconstruction: a comparison of three alternatives [Elektronische Daten] [Alaa Elfeky, Wail Nasr, Alaa Khazbak, Mohamed Abdelrahman, Zaki Allam, Wahed Gareer, Hesham Elsebaey] This study aimed to evaluate the operative outcomes of using gastric pull-up (GPU), pectoralis major myocutaneous flap (PMMF), and jejunal free flap (JFF) to reconstruct the hypopharynx after resection of hypopharyngeal and cervical esophageal carcinoma. Retrospective clinical study. Otolaryngology Department, Zagazig University Hospital, Egypt and Surgical Department, National Cancer Institute, Cairo, Egypt. Records of 104 patients who underwent resection of carcinoma of the hypopharynx and cervical esophagus were reviewed to determine the indications for radical resection, location, and stage of the primary tumor, gross and pathological surgical resection margins, operative complications, morbidity, and mortality. Reconstruction was performed using the GPU for group (1) (n=33), PMMF for group (2) (n=34), and JFF for group (3) (n=37). The hypopharynx was the most common primary tumor site for group (2) and group (3) whereas group (1) had lesions more frequently in the cervical esophagus. The overall postoperative morbidity rate was 20.2% with a perioperative mortality rate of 6.7% and there was no significant difference between the three groups. There was no graft necrosis in group (1) compared to 5.9% in group (2) and 5.4% in group (3). Pulmonary complications occurred commonly (30.3%) in group (1) compared to 11.8% in group (2) and 10.8% in group (3) The overall 3years survival rate was 67.3% and there was no significant difference between the three groups. The outcomes of the three techniques are equally successful when used appropriately. The nature of the defect indicates the method of reconstruction. For short reconstruction above the thoracic inlet, PMMF or JFF are equally effective and in tumors requiring total esophagectomy, GPA is indicated. Springer-Verlag Berlin Heidelberg, 2014 Cancer nationallicence Myocutaneous flaps nationallicence Visceral transposition nationallicence Hypopharynx nationallicence Pharyngolaryngectomy nationallicence Elfeky Alaa Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Zagazig University, 4419, Zagazig, Egypt aut Nasr Wail Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Zagazig University, 4419, Zagazig, Egypt aut Khazbak Alaa Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Zagazig University, 4419, Zagazig, Egypt aut Abdelrahman Mohamed Department of Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut Allam Zaki Department of Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut Gareer Wahed Department of Surgery, National Cancer Institute, Cairo, Egypt aut Elsebaey Hesham Department of Vascular and Reconstructive Surgery, National Cancer Institute, Cairo, Egypt aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 3045-3050 0937-4477 272:10<3045 2015 272 405 https://doi.org/10.1007/s00405-014-3306-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3306-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Elfeky Alaa Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Zagazig University, 4419, Zagazig, Egypt aut NATIONALLICENCE 700 1- Nasr Wail Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Zagazig University, 4419, Zagazig, Egypt aut NATIONALLICENCE 700 1- Khazbak Alaa Department of Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine, Zagazig University, 4419, Zagazig, Egypt aut NATIONALLICENCE 700 1- Abdelrahman Mohamed Department of Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- Allam Zaki Department of Surgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt aut NATIONALLICENCE 700 1- Gareer Wahed Department of Surgery, National Cancer Institute, Cairo, Egypt aut NATIONALLICENCE 700 1- Elsebaey Hesham Department of Vascular and Reconstructive Surgery, National Cancer Institute, Cairo, Egypt aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/10(2015-10-01), 3045-3050 0937-4477 272:10<3045 2015 272 405