caa a22 4500 606185801 CHVBK 20210128100833.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00405-014-3060-0 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3060-0 Sethi Neeraj Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St James' University Building, LS9 7TF, Leeds, West Yorkshire, UK aut The significance of osteitis in rhinosinusitis [Elektronische Daten] [Neeraj Sethi] Rhinosinusitis is a disease of multifactorial aetiology. As a profession our insight into this pathological process has progressed enormously over the last few decades. The contribution from environmental, host immunity, microbiology and anatomical factors is well recognised, if not completely understood. The involvement of underlying bone in rhinosinusitis was first recognised experimentally in animals and has subsequently been highlighted as a potentially significant finding in humans with CRS. In this review, the role of bone in chronic rhinosinusitis and the evidence behind that role are discussed. Both histological and radiological findings are presented and the subsequent potential clinical impact and relevance of osteitis in rhinosinusitis patients. Future pathways for research to add to the current knowledge of the impact of bony involvement are also discussed. Springer-Verlag Berlin Heidelberg, 2014 Rhinosinusitis nationallicence Osteitis nationallicence Radiology nationallicence Histology nationallicence European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/4(2015-04-01), 821-826 0937-4477 272:4<821 2015 272 405 https://doi.org/10.1007/s00405-014-3060-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3060-0 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Sethi Neeraj Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, St James' University Building, LS9 7TF, Leeds, West Yorkshire, UK aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/4(2015-04-01), 821-826 0937-4477 272:4<821 2015 272 405