caa a22 4500 606185895 CHVBK 20210128100833.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00405-014-3053-z doi (NATIONALLICENCE)springer-10.1007/s00405-014-3053-z Salivary mucoepidermoid carcinoma revisited [Elektronische Daten] [Andrés Coca-Pelaz, Juan Rodrigo, Asterios Triantafyllou, Jennifer Hunt, Alessandra Rinaldo, Primož Strojan, Missak Haigentz Jr., William Mendenhall, Robert Takes, Vincent Vander Poorten, Alfio Ferlito] Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations. Springer-Verlag Berlin Heidelberg, 2014 Head and neck nationallicence Mucoepidermoid carcinoma nationallicence Pathology nationallicence Prognosis nationallicence Salivary glands nationallicence Therapy nationallicence Coca-Pelaz Andrés Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain aut Rodrigo Juan Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain aut Triantafyllou Asterios Oral Pathology, School of Dentistry, University of Liverpool, Liverpool, UK aut Hunt Jennifer Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, USA aut Rinaldo Alessandra University of Udine School of Medicine, Piazzale S. Maria della Misericordia, 33100, Udine, Italy aut Strojan Primož Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia aut Haigentz Jr. Missak Division of Oncology, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA aut Mendenhall William Department of Radiation Oncology, University of Florida, Gainesville, FL, USA aut Takes Robert Department of Otolaryngology-Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands aut Vander Poorten Vincent Department of Otorhinolaryngology-Head and Neck Surgery, Leuven Cancer Institute, University Hospitals Leuven - KULeuven, Leuven, Belgium aut Ferlito Alfio University of Udine School of Medicine, Piazzale S. Maria della Misericordia, 33100, Udine, Italy aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/4(2015-04-01), 799-819 0937-4477 272:4<799 2015 272 405 https://doi.org/10.1007/s00405-014-3053-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3053-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Coca-Pelaz Andrés Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain aut NATIONALLICENCE 700 1- Rodrigo Juan Department of Otolaryngology, Hospital Universitario Central de Asturias, Oviedo, Spain aut NATIONALLICENCE 700 1- Triantafyllou Asterios Oral Pathology, School of Dentistry, University of Liverpool, Liverpool, UK aut NATIONALLICENCE 700 1- Hunt Jennifer Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, USA aut NATIONALLICENCE 700 1- Rinaldo Alessandra University of Udine School of Medicine, Piazzale S. Maria della Misericordia, 33100, Udine, Italy aut NATIONALLICENCE 700 1- Strojan Primož Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia aut NATIONALLICENCE 700 1- Haigentz Jr Missak Division of Oncology, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA aut NATIONALLICENCE 700 1- Mendenhall William Department of Radiation Oncology, University of Florida, Gainesville, FL, USA aut NATIONALLICENCE 700 1- Takes Robert Department of Otolaryngology-Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands aut NATIONALLICENCE 700 1- Vander Poorten Vincent Department of Otorhinolaryngology-Head and Neck Surgery, Leuven Cancer Institute, University Hospitals Leuven - KULeuven, Leuven, Belgium aut NATIONALLICENCE 700 1- Ferlito Alfio University of Udine School of Medicine, Piazzale S. Maria della Misericordia, 33100, Udine, Italy aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/4(2015-04-01), 799-819 0937-4477 272:4<799 2015 272 405