caa a22 4500 606186077 CHVBK 20210128100834.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00405-014-3155-7 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3155-7 The role of elastography in evaluating thyroid nodules: a literature review and meta-analysis [Elektronische Daten] [Vik Veer, Srikanth Puttagunta] To appraise the literature for studies involving the use of elastography to diagnose thyroid nodule pathology. Two independent reviewers performed a systematic review of the English medical literature for studies involving elastography diagnosing thyroid nodule pathology. Data gleaned from this process was used in a meta-analysis to summarise the results. Thirty-eight studies were used in the meta-analysis totalling 5,942 thyroid nodules examined with elastography. The pooled results were sensitivity=87.0% (95% confidence intervals (CI)=86.2-87.9%), specificity=80.6% (CI=79.5-81.6%), positive predictive value (PPV)=48.9% (CI=47.6-50.2%), negative predictive value (NPV)=96.7% (CI=96.2-97.1%), diagnostic accuracy=81.7% (CI=80.7-82.7%). Subgroup analysis of the data is also presented. Elastography has its limitations in the diagnosis of thyroid nodules; however, its high NPV is increasingly being used as an important investigation and may allow a reduction in the number of hemi-thyroidectomies with benign pathology. Subgroup analysis suggests that elastography techniques where compressive force is performed in a non-user-dependant method results in improved final results. Springer-Verlag Berlin Heidelberg, 2014 Thyroid nodules nationallicence Ultrasound nationallicence Elastography nationallicence Veer Vik James Cook University Hospital, Marton Rd, TS4 3BW, Middlesbrough, England, UK aut Puttagunta Srikanth Glasgow Royal Infirmary, 84 Castle St, Glasgow, G4 0SF, Glasgow City, Scotland, UK aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1845-1855 0937-4477 272:8<1845 2015 272 405 https://doi.org/10.1007/s00405-014-3155-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3155-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Veer Vik James Cook University Hospital, Marton Rd, TS4 3BW, Middlesbrough, England, UK aut NATIONALLICENCE 700 1- Puttagunta Srikanth Glasgow Royal Infirmary, 84 Castle St, Glasgow, G4 0SF, Glasgow City, Scotland, UK aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1845-1855 0937-4477 272:8<1845 2015 272 405