caa a22 4500 606186158 CHVBK 20210128100835.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00405-014-3126-z doi (NATIONALLICENCE)springer-10.1007/s00405-014-3126-z Diagnosis and management of multiple paragangliomas of the head and neck [Elektronische Daten] [Anna Szymańska, Marcin Szymański, Elżbieta Czekajska-Chehab, Wiesław Gołąbek, Małgorzata Szczerbo-Trojanowska] Paragangliomas (PGs) are slowly growing, usually benign neoplasms. The aim of the study was to analyze the incidence, diagnostic and therapeutic management of patients with multiple paragangliomas of the head and neck. A retrospective review of the records of 84 patients with head and neck PGs, diagnosed and treated in our institution was performed for the years 1983-2013 to identify patients with multiple tumors. Fourteen (16.6%) patients developed multiple PGs, synchronous or metachronous, within 4-21years of follow-up. Clinical data of these patients were reviewed to evaluate the diagnosis, location, stage and management strategy. There was a total number of 37 tumors in 14 patients. There were 20/37 (54.0%) carotid PGs, 9/37 (24.3%) jugular PGs and 8/37 (21.7%) vagal PGs. Carotid PGs were observed in 12/14 (86%) patients and in 8/14 (57%) cases bilateral tumors occurred. Vagal PGs developed in 7/14 (50%) patients and bilateral tumors were found in 1/14 (7%) case. Jugular PGs occurred in 9/14 (64%) patients. There were 30 synchronous tumors and seven metachronous PGs diagnosed 2-18years after removal of the first tumor. Single metachronous mediastinal PG occurred. All patients had at least one tumor removed, with histopathological confirmation of the diagnosis. One patient had positive history of familial PGs. Carotid PGs are most common multiple paragangliomas. Radiological survey of the head and neck is required to detect multicentric tumors. Metachronous mediastinal and abdominal tumors may occur. Regular, prolonged follow-up is essential to identify metachronous PGs and possible postoperative gradual ICA occlusion. The Author(s), 2014 Imaging nationallicence Metachronous nationallicence Multiple tumors nationallicence Paraganglioma nationallicence Surgery nationallicence Synchronous nationallicence Szymańska Anna Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut Szymański Marcin Department of Otolaryngology, Head and Neck Surgery, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut Czekajska-Chehab Elżbieta Department of General Radiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut Gołąbek Wiesław Professor Emeritus, Department of Otolaryngology, Head and Neck Surgery, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut Szczerbo-Trojanowska Małgorzata Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1991-1999 0937-4477 272:8<1991 2015 272 405 https://doi.org/10.1007/s00405-014-3126-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3126-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Szymańska Anna Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut NATIONALLICENCE 700 1- Szymański Marcin Department of Otolaryngology, Head and Neck Surgery, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut NATIONALLICENCE 700 1- Czekajska-Chehab Elżbieta Department of General Radiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut NATIONALLICENCE 700 1- Gołąbek Wiesław Professor Emeritus, Department of Otolaryngology, Head and Neck Surgery, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut NATIONALLICENCE 700 1- Szczerbo-Trojanowska Małgorzata Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Jaczewskiego 8, 20-154, Lublin, Poland aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1991-1999 0937-4477 272:8<1991 2015 272 405