caa a22 4500 60618631X CHVBK 20210128100835.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00405-014-2982-x doi (NATIONALLICENCE)springer-10.1007/s00405-014-2982-x Hyaluronic acid fat graft myringoplasty vs fat patch fat graft myringoplasty [Elektronische Daten] [Musaed Alzahrani, Issam Saliba] We aim to compare the hyaluronic acid to fat graft myringoplasty (HAFGM) technique to a recently described modified-FGM (M-FGM) in the repair of tympanic membrane perforation (TMP). We also aim to evaluate the hearing level improvement postoperatively. We conducted a prospective study in an adult tertiary care center between 2012 and 2013. Adult patients presenting with simple TMP were operated on randomly using either HAFGM or M-FGM under local anesthesia in outpatients' settings. Success was considered when complete closure is achieved. Audiometric parameters were evaluated pre and postoperatively. Twenty-four patients were included in the study (HAFGM: 10 patients and M-FGM: 14 patients). Complete closure was achieved in 80% in HAFGM vs 42.8% in the M-FGM (p=0.03). The study was abandoned due to the low success rate in first 14 patients of the M-FGM group. The pure tone audiometry was improved postoperatively in the HAFGM only. The study was aborted because of the unsatisfactory obtained results using the MFGM. It also shows the beneficial effect of hyaluronic acid application to FGM for a successful TMP repair. Springer-Verlag Berlin Heidelberg, 2014 Tympanic membrane perforations nationallicence Myringoplasty nationallicence Hyaluronic acid nationallicence Hearing loss nationallicence Fat graft nationallicence HAFGM nationallicence Alzahrani Musaed Division of Otolaryngology, Head and Neck Surgery, Montreal University Hospital Center (CHUM), University of Montreal, 1560, rue Sherbrooke East, H2L 4M1, Montreal, QC, Canada aut Saliba Issam Division of Otolaryngology, Head and Neck Surgery, Montreal University Hospital Center (CHUM), University of Montreal, 1560, rue Sherbrooke East, H2L 4M1, Montreal, QC, Canada aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1873-1877 0937-4477 272:8<1873 2015 272 405 https://doi.org/10.1007/s00405-014-2982-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-2982-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Alzahrani Musaed Division of Otolaryngology, Head and Neck Surgery, Montreal University Hospital Center (CHUM), University of Montreal, 1560, rue Sherbrooke East, H2L 4M1, Montreal, QC, Canada aut NATIONALLICENCE 700 1- Saliba Issam Division of Otolaryngology, Head and Neck Surgery, Montreal University Hospital Center (CHUM), University of Montreal, 1560, rue Sherbrooke East, H2L 4M1, Montreal, QC, Canada aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1873-1877 0937-4477 272:8<1873 2015 272 405