caa a22 4500 606186352 CHVBK 20210128100836.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s00405-014-3107-2 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3107-2 Absorbable and nonabsorbable packing after functional endoscopic sinus surgery: systematic review and meta-analysis of outcomes [Elektronische Daten] [Tang-Chuan Wang, Chih-Jaan Tai, Yung-An Tsou, Li-Tai Tsai, Yu-Fen Li, Ming-Hsui Tsai] The purpose of the study was to perform a systematic review and meta-analysis of the literature to compare the efficacy (and other postoperative outcomes) of nonabsorbable versus absorbable nasal packing after functional endoscopic sinus surgery (FESS) for the treatment of chronic rhinosinusitis. Studies were considered for inclusion if they were published in English language, were randomized clinical trials, and reported on outcomes following postoperative synechia. The primary outcome for meta-analysis was the incidence of postoperative synechia; pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using fixed-effects models. Five studies, involving 241 nasal cavities in each treatment group, were included in the systematic review. The prevalence of synechia ranged from 4.6 to 8.0% in the absorbable groups and from 8.0 to 35.7% in the nonabsorbable groups. Postoperative bleeding was lower in the absorbable groups, whereas there was no clear finding regarding postoperative pain. Postoperative edema was generally similar between groups. There were no consistent findings regarding bleeding and pain on packing removal. Two studies using the same type of packing material were included in the meta-analysis. The combined OR (0.33, 95% CI 0.04-2.78) for postoperative synechia did not significantly favor (P=0.308) absorbable packing over nonabsorbable packing. Although there is some evidence in the available literature that absorbable nasal packing may provide superior outcomes to nonabsorbable packing after FESS, the lack of homogeneity between studies makes definitive conclusions impossible. Further randomized clinical trials are needed to compare the efficacy of different types of absorbable nasal packing for preventing synechia after FESS. The Author(s), 2014 Absorbable nationallicence Efficacy nationallicence Epistaxis nationallicence FESS nationallicence Functional endoscopic sinus surgery nationallicence Meta-analysis nationallicence Nasal nationallicence Nonabsorbable nationallicence Packing nationallicence Synechia nationallicence Wang Tang-Chuan Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut Tai Chih-Jaan Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut Tsou Yung-An Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut Tsai Li-Tai Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut Li Yu-Fen Graduate Institute of Biostatistics, China Medical University, Taichung, Taiwan aut Tsai Ming-Hsui Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1825-1831 0937-4477 272:8<1825 2015 272 405 https://doi.org/10.1007/s00405-014-3107-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3107-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wang Tang-Chuan Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut NATIONALLICENCE 700 1- Tai Chih-Jaan Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut NATIONALLICENCE 700 1- Tsou Yung-An Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut NATIONALLICENCE 700 1- Tsai Li-Tai Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut NATIONALLICENCE 700 1- Li Yu-Fen Graduate Institute of Biostatistics, China Medical University, Taichung, Taiwan aut NATIONALLICENCE 700 1- Tsai Ming-Hsui Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/8(2015-08-01), 1825-1831 0937-4477 272:8<1825 2015 272 405