caa a22 4500 606186379 CHVBK 20210128100836.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s00405-014-3050-2 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3050-2 Naso-oropharyngeal choristoma (hairy polyps): an overview and current update on presentation, management, origin and related controversies [Elektronische Daten] [Mainak Dutta, Soham Roy, Soumya Ghatak] This review presents a comprehensive and updated overview of bigerminal choristomas (hairy polyps) of naso-oropharynx/oral cavity, and discusses the controversies related to nosology and origin from a clinico-embryologic perspective. English-language texts of the last 25years (January 1989-January 2014) were collected from the PubMed/MEDLINE database using the given keywords. Of the 330 records, 64 full-text articles (mostly case reports/series) were selected, incorporating clinical data from 78 patients, after screening through duplicates and the given exclusion criteria. With the available evidence, hairy polyps appear more common than generally believed, and are increasingly being recognized as an important, often-missed cause of respiratory distress and feeding difficulty in neonates and infants. Such a child without any apparent cause should be examined with flexible nasopharyngoscope to specifically look for hairy polyps which might be life-threatening, especially when small. The female preponderance as believed today has been found to be an overestimation in this review. These lesions are characteristically composed of mature ectodermal and mesodermal tissue derivatives presenting as heterotopic masses, hence termed choristoma. However, little is known about their origin, and whether they are developmental malformations or primitive teratomas is debatable. Involvement of Eustachian tube and tonsils as predominant subsites and the speculated molecular embryogenesis link hairy polyps to the development of the first and second pharyngeal arches. They are exceptionally rare in adults, but form a distinct entity in this age-group and could be explained as delayed pluripotent cell morphogenesis or focal neoplastic malformations, keeping with the present-day understandings of the expanded "teratoma family”. Springer-Verlag Berlin Heidelberg, 2014 Choristoma nationallicence Dermoid nationallicence Hairy polyp nationallicence Congenital nationallicence Nasopharynx nationallicence Oropharynx nationallicence Oral cavity nationallicence Eustachian tube nationallicence Adult nationallicence Embryogenesis nationallicence Dutta Mainak Department of Otorhinolaryngology and Head-Neck Surgery, Medical College and Hospital, 88, College Street, 700073, Kolkata, West Bengal, India aut Roy Soham Department of Otorhinolaryngology-Head and Neck Surgery, Director of Pediatric Otolaryngology-Head and Neck Surgery, Children's Memorial Hermann Hospital, University of Texas Medical School at Houston, Houston, TX, USA aut Ghatak Soumya Department of Otorhinolaryngology and Head-Neck Surgery, R. G. Kar Medical College and Hospital, 700004, Kolkata, West Bengal, India aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/5(2015-05-01), 1047-1059 0937-4477 272:5<1047 2015 272 405 https://doi.org/10.1007/s00405-014-3050-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3050-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Dutta Mainak Department of Otorhinolaryngology and Head-Neck Surgery, Medical College and Hospital, 88, College Street, 700073, Kolkata, West Bengal, India aut NATIONALLICENCE 700 1- Roy Soham Department of Otorhinolaryngology-Head and Neck Surgery, Director of Pediatric Otolaryngology-Head and Neck Surgery, Children's Memorial Hermann Hospital, University of Texas Medical School at Houston, Houston, TX, USA aut NATIONALLICENCE 700 1- Ghatak Soumya Department of Otorhinolaryngology and Head-Neck Surgery, R. G. Kar Medical College and Hospital, 700004, Kolkata, West Bengal, India aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/5(2015-05-01), 1047-1059 0937-4477 272:5<1047 2015 272 405