caa a22 4500 606186506 CHVBK 20210128100836.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s00405-014-3030-6 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3030-6 Prognostic factors of quality of life after transoral laser microsurgery for laryngeal cancer [Elektronische Daten] [Isabel Vilaseca, Manuel Bernal-Sprekelsen, Ruth Him, Alexandra Mandry, Eduardo Lehrer, José Blanch] We aimed to evaluate factors influencing quality of life (QOL) after transoral laser microsurgery (TLM) of laryngeal cancer. Four hundred and one consecutive disease-free patients were evaluated 1year after treatment using the University of Washington-QOL v4, the SF-12 (short form of SF-36), and a questionnaire about self-rated health status. The importance of age, gender, tumor location, tumor size, tumor stage, neck dissection and adjuvant treatment were evaluated. One year after TLM patients had a good QOL, with only 6% of patients reporting a worsening in their health status. Radiation therapy (p=0.000) and neck dissection (p=0.000) were negative factors for disease-specific QOL, whereas age ≥70 (p=0.01) was a positive independent factor for mental score of SF-12. Speech was negatively influenced by tumor size (p=0.001) as was swallowing by age (p=0.001) and postoperative radiation (p=0.000). Patients treated with TLM present a good QOL 1year after surgery. Radiation and neck dissection negatively impact QOL. Elderly patients cope better with their disabilities. Springer-Verlag Berlin Heidelberg, 2014 Quality of life nationallicence Transoral laser microsurgery nationallicence Laryngeal carcinoma nationallicence Head and neck cancer nationallicence Vilaseca Isabel Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut Bernal-Sprekelsen Manuel Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut Him Ruth Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut Mandry Alexandra Department of Head and Neck Surgery, Instituto de Oncología Ángel H. Roffo, Buenos Aires, Argentina aut Lehrer Eduardo Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut Blanch José Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/5(2015-05-01), 1203-1210 0937-4477 272:5<1203 2015 272 405 https://doi.org/10.1007/s00405-014-3030-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3030-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Vilaseca Isabel Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Bernal-Sprekelsen Manuel Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Him Ruth Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Mandry Alexandra Department of Head and Neck Surgery, Instituto de Oncología Ángel H. Roffo, Buenos Aires, Argentina aut NATIONALLICENCE 700 1- Lehrer Eduardo Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut NATIONALLICENCE 700 1- Blanch José Department of Otorhinolaryngology, Hospital Clínic, c/Villarroel 170, 08036, Barcelona, Spain aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/5(2015-05-01), 1203-1210 0937-4477 272:5<1203 2015 272 405