caa a22 4500 60618659X CHVBK 20210128100837.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s00405-014-3192-2 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3192-2 The comparison of the viability of crushed, morselized and diced cartilage grafts: a confocal microscopic study [Elektronische Daten] [Gurkan Kayabasoglu, Elvan Ozbek, Sevinc Yanar, Fikrettin Sahin, Osman Keles, Mahmut Yilmaz, Mehmet Guven] To compare the cellular viability of diced, crushed, and morselized cartilage used in nasal surgeries. In this study, cartilage was extracted from the ears of seven New Zealand rabbits and was subsequently either diced, crushed or morselized to an amorphous state, or left unmodified. The four types of grafts were then implanted in the back regions of the rabbits. After 3months, the cellular viability from four groups was compared to a control group using confocal microscopy. Analysis of the data obtained from the enumeration of live cells showed no statistically significant difference between the unmodified graft group and the control group. The diced, crushed, and morselized cartilage groups did show a statistically significant difference in terms of live cell count with the highest number of live cells in diced cartilage group. A statistically significant decrease in live cell count was detected in crushed cartilage group. Our study shows that the viability of cells in diced cartilage grafts is greater than those in crushed or morselized cartilage grafts. Springer-Verlag Berlin Heidelberg, 2014 Confocal microscopy nationallicence Cartilage nationallicence Cell viability nationallicence Experimental nationallicence Rhinoplasty nationallicence Morselization nationallicence Graft nationallicence Diced nationallicence Crushing nationallicence Nasal surgery nationallicence Kayabasoglu Gurkan Department of Otorhinolaryngology, Faculty of Medicine, Sakarya University, Adnan Menderes Cad. No 145, 54100, Adapazarı, Sakarya, Turkey aut Ozbek Elvan Department of Histology and Embryology, Faculty of Medicine, Sakarya University, Adapazarı, Sakarya, Turkey aut Yanar Sevinc Department of Histology and Embryology, Faculty of Medicine, Sakarya University, Adapazarı, Sakarya, Turkey aut Sahin Fikrettin Department of Genetics and Bioengineering, Faculty of Engineering and Architecture, Yeditepe University, Istanbul, Turkey aut Keles Osman Department of Histology and Embryology, Faculty of Medicine, Ataturk University, Erzurum, Turkey aut Yilmaz Mahmut Department of Otorhinolaryngology, Faculty of Medicine, Sakarya University, Adnan Menderes Cad. No 145, 54100, Adapazarı, Sakarya, Turkey aut Guven Mehmet Department of Otorhinolaryngology, Faculty of Medicine, Sakarya University, Adnan Menderes Cad. No 145, 54100, Adapazarı, Sakarya, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/5(2015-05-01), 1135-1142 0937-4477 272:5<1135 2015 272 405 https://doi.org/10.1007/s00405-014-3192-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3192-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kayabasoglu Gurkan Department of Otorhinolaryngology, Faculty of Medicine, Sakarya University, Adnan Menderes Cad. No 145, 54100, Adapazarı, Sakarya, Turkey aut NATIONALLICENCE 700 1- Ozbek Elvan Department of Histology and Embryology, Faculty of Medicine, Sakarya University, Adapazarı, Sakarya, Turkey aut NATIONALLICENCE 700 1- Yanar Sevinc Department of Histology and Embryology, Faculty of Medicine, Sakarya University, Adapazarı, Sakarya, Turkey aut NATIONALLICENCE 700 1- Sahin Fikrettin Department of Genetics and Bioengineering, Faculty of Engineering and Architecture, Yeditepe University, Istanbul, Turkey aut NATIONALLICENCE 700 1- Keles Osman Department of Histology and Embryology, Faculty of Medicine, Ataturk University, Erzurum, Turkey aut NATIONALLICENCE 700 1- Yilmaz Mahmut Department of Otorhinolaryngology, Faculty of Medicine, Sakarya University, Adnan Menderes Cad. No 145, 54100, Adapazarı, Sakarya, Turkey aut NATIONALLICENCE 700 1- Guven Mehmet Department of Otorhinolaryngology, Faculty of Medicine, Sakarya University, Adnan Menderes Cad. No 145, 54100, Adapazarı, Sakarya, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/5(2015-05-01), 1135-1142 0937-4477 272:5<1135 2015 272 405