caa a22 4500 606186824 CHVBK 20210128100838.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00405-014-3094-3 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3094-3 Effects of surfactant on biofilm formation on silicone nasal splints [Elektronische Daten] [Turhan San, Omer Ertugay, Tolgahan Catli, Mustafa Acar, Cigdem Ertugay, Ilknur Dag, Cemal Cingi] Biofilms are sessile communities of bacteria embedded in self-produced extracellular polysaccharide matrix and are considered to be responsible for bacterial infections in humans. Topical surfactant use on silicone nasal splints may have a preventive effect on biofilm formation. The objective of this study is to investigate the effect of surfactant-containing nasal solutions on biofilm formation over the surface of silicone nasal splints. Forty patients were randomized after septoplasty to receive surfactant-containing saline solution (group 1) or saline without surfactant (group 2). At the postoperative 48th, 72th and 96th hours, pieces of splint samples were taken and prepared for scanning electron microscopic evaluation. Biofilm formation was observed in 3, 6 and 14 of 20 samples in group 1 (surfactant used) and 3, 14 and 20 of 20 samples in group 2 (control) at 48th, 72th and 96th hours, respectively. Biofilm formation incidences of groups at 48th hour were similar (p>0.05), whereas it was significantly lower at group 1 regarding 72th and 96th hours (p<0.05). Surfactant-containing nasal solutions have an inhibitory effect on biofilm formation over the surface of silicone nasal splints especially after 48h. Surfactant-containing nasal solutions may have an important role in nasal septal dressing in the future. Springer-Verlag Berlin Heidelberg, 2014 Biofilm nationallicence Surfactant nationallicence Nasal splint nationallicence San Turhan Department of Otolaryngology, Istanbul Medeniyet University Göztepe Training and Research Hospital, Istanbul, Turkey aut Ertugay Omer Department of Otolaryngology, Zile State Hospital, Tokat, Turkey aut Catli Tolgahan Department of Otolaryngology, Bozyaka Training and Research Hospital, Izmir, Turkey aut Acar Mustafa Department of Otolaryngology, Yunus Emre State Hospital, Eskisehir, Turkey aut Ertugay Cigdem Kulak Burun Bogaz Klinigi İstanbul Hastanesi, Başkent Üniversitesi, 34662, Istanbul, Turkey aut Dag Ilknur Electron Microscope Laboratory, Medical Faculty, Eskişehir Osmangazi University, Eskisehir, Turkey aut Cingi Cemal Department of Otorhinolaryngology, Medical Faculty, Osmangazi University, Eskisehir, Turkey aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 345-349 0937-4477 272:2<345 2015 272 405 https://doi.org/10.1007/s00405-014-3094-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3094-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- San Turhan Department of Otolaryngology, Istanbul Medeniyet University Göztepe Training and Research Hospital, Istanbul, Turkey aut NATIONALLICENCE 700 1- Ertugay Omer Department of Otolaryngology, Zile State Hospital, Tokat, Turkey aut NATIONALLICENCE 700 1- Catli Tolgahan Department of Otolaryngology, Bozyaka Training and Research Hospital, Izmir, Turkey aut NATIONALLICENCE 700 1- Acar Mustafa Department of Otolaryngology, Yunus Emre State Hospital, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Ertugay Cigdem Kulak Burun Bogaz Klinigi İstanbul Hastanesi, Başkent Üniversitesi, 34662, Istanbul, Turkey aut NATIONALLICENCE 700 1- Dag Ilknur Electron Microscope Laboratory, Medical Faculty, Eskişehir Osmangazi University, Eskisehir, Turkey aut NATIONALLICENCE 700 1- Cingi Cemal Department of Otorhinolaryngology, Medical Faculty, Osmangazi University, Eskisehir, Turkey aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 345-349 0937-4477 272:2<345 2015 272 405