caa a22 4500 606186840 CHVBK 20210128100838.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00405-014-2968-8 doi (NATIONALLICENCE)springer-10.1007/s00405-014-2968-8 The presentation, natural history and outcome of T1 a/b thyroid cancer with regard to new grading systems [Elektronische Daten] [Joel Smith, Neil Sharma, Paul Nankivell, John Watkinson] Introduction: The seventh edition tumor, node metastasis (TNM) classifies tumors <10mm as T1a and tumors between 10mm and 20mm as T1b. Previous editions of the TNM staging system did not differentiate these lesions. We compare new classification in terms of presentation and outcome. Methods: Early thyroid cancers that were previously staged under the TNM sixth edition were re-staged using the TNM seventh edition to identify whether the new staging system differentiated lesions in terms of presentation and outcome. Differences in presentation, rates of recurrent disease and surgical complications were recorded and compared. Results: Of 1,415 thyroid operations, 369 were for malignant disease and there were 220 papillary carcinomas. There were 35 T1a/b lesions accounting for 11% of malignancies with no increasing incidence. Reclassification showed 64% T1a and 36% T1b lesions. There were no differences in presentation. Outcomes in terms of persistent or recurrent disease were the same after median follow up was 6.8years. Conclusion: Isolated T1a/b thyroid cancer made up only a small proportion of malignancies, the majority of which were discovered incidentally. We have not seen the increase in early lesions reported elsewhere. In our series, the seventh TNM edition did not differentiate early lesions and we ultimately feel that parameters other than size of primary lesion are likely to be of greater importance in determining prognosis. Springer-Verlag Berlin Heidelberg, 2014 Early-stage thyroid cancer prognosis nationallicence Early-stage thyroid cancer management nationallicence Papillary microcarcinoma nationallicence TNM staging seventh edition nationallicence Smith Joel Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut Sharma Neil Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut Nankivell Paul Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut Watkinson John Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 439-444 0937-4477 272:2<439 2015 272 405 https://doi.org/10.1007/s00405-014-2968-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-2968-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Smith Joel Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 700 1- Sharma Neil Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 700 1- Nankivell Paul Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 700 1- Watkinson John Department of Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital Birmingham, Mindelsohn Way, Edgbaston, B15 2WB, Birmingham, UK aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 439-444 0937-4477 272:2<439 2015 272 405