caa a22 4500 606186883 CHVBK 20210128100838.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00405-013-2853-x doi (NATIONALLICENCE)springer-10.1007/s00405-013-2853-x Effects of oral contraceptives on selected parameters of the homeostatic control system in young women having a sudden disorder of the auditory and/or balance system [Elektronische Daten] [Joanna Urbaniak, Hanna Zielińska-Bliźniewska, Jarosław Miłoński, Piotr Pietkiewicz, Krzysztof Kuśmierczyk, Jurek Olszewski] The purpose of the paper was to assess the effects of oral contraceptives on selected parameters of the homeostatic control system in women having a sudden disorder of the auditory and/or balance system. The study included 105 young women divided into two groups: Group I—52 women with the disorder of the auditory and/or balance system using hormonal contraceptives for at least 2months, aged 20-49; and Group II—53 women without any disorder of the auditory and/or balance system using hormonal contraceptives for at least 2months, aged 18-40. The patients included in the study underwent a full otoneurological evaluation, detailed laryngological diagnostics and an evaluation of selected parameters of the homeostatic control system—fibrinogen level, D-dimer level, evaluation of APTT and PT indicator, plasma estradiol and progesterone with the Roche Cobas analyser by means of chemiluminescence. The vertigo occurring in the study group was most often central (59.6% of cases), mixed with compensation in 36.6% of cases, and peripheral only in 3.8% of cases, indicating labyrinth damage in 40.4% of cases. An analysis of the progesterone level, considering the menstrual cycle phase in the group, showed that its value was abnormal in 51.0% of women in the study group and 47.1% in the control group. In their own studies, the authors observed that the estradiol level in the plasma, considering the menstrual cycle phase in the study group, was abnormal in 41.2% of women and that the differences in its concentration were statistically significant in the study and control groups (p=0.005), which may have a negative impact on the possibility of a thromboembolic episode. The Author(s), 2013 Oral contraceptives nationallicence Parameters of the homeostatic control system nationallicence Auditory and balance disorders nationallicence Urbaniak Joanna Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut Zielińska-Bliźniewska Hanna Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut Miłoński Jarosław Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut Pietkiewicz Piotr Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut Kuśmierczyk Krzysztof Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut Olszewski Jurek Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 321-326 0937-4477 272:2<321 2015 272 405 https://doi.org/10.1007/s00405-013-2853-x text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-013-2853-x text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Urbaniak Joanna Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut NATIONALLICENCE 700 1- Zielińska-Bliźniewska Hanna Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut NATIONALLICENCE 700 1- Miłoński Jarosław Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut NATIONALLICENCE 700 1- Pietkiewicz Piotr Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut NATIONALLICENCE 700 1- Kuśmierczyk Krzysztof Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut NATIONALLICENCE 700 1- Olszewski Jurek Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, Żeromskiego 113, 90-549, Lodz, Poland aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 321-326 0937-4477 272:2<321 2015 272 405