caa a22 4500 606186891 CHVBK 20210128100838.0 cr unu---uuuuu 210128e20150201xx s 000 0 eng 10.1007/s00405-014-3109-0 doi (NATIONALLICENCE)springer-10.1007/s00405-014-3109-0 Assessment of quality-of-life outcomes after surgery for nasal polyposis with the DyNaChron questionnaire [Elektronische Daten] [Duc Nguyen, Francis Guillemin, Fabien Arous, Roger Jankowski] This prospective study assesses outco mes at 6weeks and 7months after radical ethmoid surgery in 65 patients with nasal polyposis using a new and detailed instrument, the DyNaChron questionnaire, which was filled in the day prior to surgery and at 6weeks and 7months after surgery at follow-up visits. Before surgery, the leading bothersome symptoms were olfactory disturbances (7.74±2.81) and nasal obstruction (6.66±2.28). After surgery (6th week and 7th month), there was a clear improvement of all symptoms including nasal obstruction, olfactory disturbances, anterior rhinorrhea, postnasal discharge, facial pain/headache and cough in comparison to baseline (p<0.0001). Nasal obstruction was the most improved symptom (effect size of 2.24). At 7th post-operative month, the sense of smell continued to improve slightly. By contrast, the postnasal discharge score that was significantly improved at 6th post-operative week tended to worsen at 7months (p=0.0045). Before surgery, strong psychosocial impacts were observed in association with nasal obstruction and anterior rhinorrhea. The physical impacts of each symptom were proportionally correlated to the symptom score before and after surgery. The quality of life (QOL) related to each symptom was clearly better at 6weeks and remained steady at 7months after surgery. In conclusion, olfactory disorders and postnasal rhinorrhea were the main remaining symptoms after sinus surgery despite a global improvement of symptoms and quality of life. The earlier time point to stabilize QOL outcomes of endoscopic sinus surgery could be suggested at 6weeks after surgery. Springer-Verlag Berlin Heidelberg, 2014 Nasal polyposis nationallicence DyNaChron questionnaire nationallicence Quality of life nationallicence Endoscopic sinus surgery (ESS) nationallicence Nguyen Duc Departments of ENT, Head and Neck Surgery, Nancy University Hospital - Service d'Otorhinolaryngologie et Chirurgie Cervico-Faciale, Hôpital Central, Centre Hospitalier Universitaire de Nancy, 29, Av. du Maréchal de Lattre de Tassigny, 54000, Nancy, France aut Guillemin Francis Lorraine University, Paris Descartes University, EA 4360 Apemac, Nancy, France aut Arous Fabien Faculty of Medicine, University of Lorraine, Nancy, France aut Jankowski Roger Departments of ENT, Head and Neck Surgery, Nancy University Hospital - Service d'Otorhinolaryngologie et Chirurgie Cervico-Faciale, Hôpital Central, Centre Hospitalier Universitaire de Nancy, 29, Av. du Maréchal de Lattre de Tassigny, 54000, Nancy, France aut European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 367-375 0937-4477 272:2<367 2015 272 405 https://doi.org/10.1007/s00405-014-3109-0 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00405-014-3109-0 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nguyen Duc Departments of ENT, Head and Neck Surgery, Nancy University Hospital - Service d'Otorhinolaryngologie et Chirurgie Cervico-Faciale, Hôpital Central, Centre Hospitalier Universitaire de Nancy, 29, Av. du Maréchal de Lattre de Tassigny, 54000, Nancy, France aut NATIONALLICENCE 700 1- Guillemin Francis Lorraine University, Paris Descartes University, EA 4360 Apemac, Nancy, France aut NATIONALLICENCE 700 1- Arous Fabien Faculty of Medicine, University of Lorraine, Nancy, France aut NATIONALLICENCE 700 1- Jankowski Roger Departments of ENT, Head and Neck Surgery, Nancy University Hospital - Service d'Otorhinolaryngologie et Chirurgie Cervico-Faciale, Hôpital Central, Centre Hospitalier Universitaire de Nancy, 29, Av. du Maréchal de Lattre de Tassigny, 54000, Nancy, France aut NATIONALLICENCE 773 0- European Archives of Oto-Rhino-Laryngology Springer Berlin Heidelberg 272/2(2015-02-01), 367-375 0937-4477 272:2<367 2015 272 405